A Lorentz-force actuated controllable needle-free drug delivery system
Author(s)Hemond, Brian D. (Brian David Thomson)
Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.
Ian W. Hunter.
MetadataShow full item record
The advantages of delivering injections via needle-free methods are numerous. However, conventional methods for needle-free injection lack sufficient control over depth of penetration and shape of injection. Thus, a needle-free injector was designed, constructed, and tested, using a controllable linear Lorentz-force actuator. This actuator allows rapid control of the injection pressure during injections. Using this device, precise control over delivery parameters can be achieved. In addition, several portable power systems for this injector were developed, allowing the energy-intensive needle-free injector to be used in the field. The injector design was tested for repeatability and use for both in-vitro and in-vivo testing on murine tissue using a bacterial collagenase.
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, June 2004; and, (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, February 2006.Includes bibliographical references (leaves 89-90).
DepartmentMassachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Massachusetts Institute of Technology
Electrical Engineering and Computer Science.