Computer-Aided Drug Target Search
Author(s)Chen, Yuzong; Li, Zerong; Ung, C.Y.
Identification of the unknown targets of drugs, investigative drugs and herbal ingredients is an important task in drug discovery. It can potentially help in several aspects including: (1) determination of unknown therapeutic mechanism of certain drugs and medicinal herbs, (2) prediction of drug toxicity and side effect, and (3) analysis of protein-mediated pharmacokinetic properties of drugs. Here, a computer-aided drug target search method and its validation studies are presented.
Molecular Engineering of Biological and Chemical Systems (MEBCS);
investigative drugs, medicinal herbs, therapeutic mechanism, drug toxicity, protein-mediated pharmacokinetic properties, drug target search