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dc.contributor.advisorJongyoon Han.en_US
dc.contributor.authorBow, Hansen Changen_US
dc.contributor.otherMassachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.en_US
dc.date.accessioned2007-07-18T13:12:41Z
dc.date.available2007-07-18T13:12:41Z
dc.date.copyright2006en_US
dc.date.issued2006en_US
dc.identifier.urihttp://hdl.handle.net/1721.1/37934
dc.descriptionThesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2006.en_US
dc.descriptionIncludes bibliographical references (p. 59-60).en_US
dc.description.abstractExperimental studies were performed to evaluate methods of improving separation resolution and speed in microfabricated nanofilter arrays. Experiment parameters investigated include electric field strength, nanofilter geometry, and buffer concentration. DNA polymers of size 25-1000 base pairs were the subject of our study. We concluded that increasing electric field strength resulted in inferior separation for larger DNA polymers (400-1000 bp). Additionally, we quantified the improvement in resolution of smaller nanofilter pores and lower buffer concentration. A theoretical model based on Macrotransport Theory was developed to estimate average species velocity and peak dispersion.en_US
dc.description.statementofresponsibilityby Hansen Chang Bow.en_US
dc.format.extent60 p.en_US
dc.language.isoengen_US
dc.publisherMassachusetts Institute of Technologyen_US
dc.rightsM.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.en_US
dc.rights.urihttp://dspace.mit.edu/handle/1721.1/7582
dc.subjectElectrical Engineering and Computer Science.en_US
dc.titleCharacterization of nanofilter arrays for small molecule separationen_US
dc.typeThesisen_US
dc.description.degreeS.M.en_US
dc.contributor.departmentMassachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.en_US
dc.identifier.oclc143822801en_US


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