Show simple item record

dc.contributor.advisorMichael M.J. Fischer.en_US
dc.contributor.authorKuo, Wen-Huaen_US
dc.contributor.otherMassachusetts Institute of Technology. Program in Science, Technology and Society.en_US
dc.coverage.spatiala-ja--- a-ch---en_US
dc.date.accessioned2007-10-19T20:29:09Z
dc.date.available2007-10-19T20:29:09Z
dc.date.copyright2005en_US
dc.date.issued2005en_US
dc.identifier.urihttp://hdl.handle.net/1721.1/39195
dc.descriptionThesis (Ph. D. in History and Social Study of Science and Technology (HASTS))--Massachusetts Institute of Technology, Program in Science, Technology and Society, 2005.en_US
dc.descriptionAlso issued in a 2 v. set, printed in leaves.en_US
dc.descriptionMIT Dewey Library copy: 2 v. set.en_US
dc.descriptionIncludes bibliographical references (p. 518-545).en_US
dc.description.abstractThis is a study of Japan and Taiwan's different responses to the expansion of the global drug industry. The thesis focuses on the problematic of "voicing," of how a state can make its interests heard in the International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). The ICH is a unique project that facilitates the formation of a single global market by creating universal standards for clinical trials and drug approvals. Tracing, through "slow motion" ethnography, step by step, why Japan claims a racial difference requires additional local clinical trials with "Asian bodies," this thesis rejects conventional interpretations of protectionism for Japan's resistance to globalization. It argues that more than protectionism is involved, and that a rich ethnographic understanding of Japan's medical infrastructure is required to understand the claim of biological, cultural, and national differences, as well as biostatistical arguments about the ambiguities of "extrapolation" of clinical data from one place to another.en_US
dc.description.abstract(cont.) The inherent ambiguities of efforts to create "bridging" studies as a temporary solution to these problematics created a deadlock in the ICH, and provided an opening for Taiwan, another Asian state, which does not enjoy formal recognition from the world, to speak for itself to this conference, and to create the fragile, but politically critical, possibility of becoming a clinical trial center for Asian populations. The language of genomics and biostatistics become in the more recent period the vehicles for both Japanese and Taiwanese efforts at "voicing" their concerns. Both genomics and biostatistics look different in these contexts than they do from the United States or European Union. In sum, (1) Japan's and Taiwan's response, as well as "global ethnographic objects" such as the ICH, provide important tools to rethink the comparative method as well as universalizing claims of harmonization. (2) Race, culture, and the nation-state are transformed as categories through the contemporary reworkings of genomics and biostatistics. (3) The thesis demonstrates that abstract accounts of the spread of clinical trials and resistance in various parts of the world are not to be trusted unless they include detailed probings of local understandings, identity issues, and problems of voicing.en_US
dc.description.statementofresponsibilityby Wen-Hua Kuo.en_US
dc.format.extent545 p.en_US
dc.language.isoengen_US
dc.publisherMassachusetts Institute of Technologyen_US
dc.rightsM.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.en_US
dc.rights.urihttp://dspace.mit.edu/handle/1721.1/7582
dc.subjectProgram in Science, Technology and Society.en_US
dc.titleJapan and Taiwan in the wake of bio-globalization : drugs, race and standardsen_US
dc.typeThesisen_US
dc.description.degreePh.D.in History and Social Study of Science and Technology (HASTSen_US
dc.contributor.departmentMassachusetts Institute of Technology. Program in Science, Technology and Society.en_US
dc.identifier.oclc67767409en_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record