Multimodal integration of EEG and MEG data using minimum ℓ₂-norm estimates

Abstract

The aim of this thesis was to study the effects of multimodal integration of electroencephalography (EEG) and magnetoencephalography (MEG) data on the minimum ℓ₂-norm estimates of cortical current densities. We investigated analytically the effect of including EEG recordings in MEG studies versus the addition of new MEG channels. To further confirm these results, clinical datasets comprising concurrent MEG/EEG acquisitions were analyzed. Minimum ℓ₂-norm estimates were computed using MEG alone, EEG alone, and the combination of the two modalities. Localization accuracy of responses to median-nerve stimulation was evaluated to study the utility of combining MEG and EEG.