Now showing items 27913-27932 of 35800

    • S-nitrosation of proteins relevant to Alzheimer's disease during early stages of neurodegeneration 

      Bhat, Vadiraja B.; Seneviratnea, Uthpala; Nott, Alexi; Ravindra, Kodihalli C.; Wishnok, John S; e.a. (National Academy of Sciences (U.S.), 2016-03)
      Protein S-nitrosation (SNO-protein), the nitric oxide-mediated posttranslational modification of cysteine thiols, is an important regulatory mechanism of protein function in both physiological and pathological pathways. A ...
    • S-nitrosation of proteins relevant to Alzheimer’s disease during early stages of neurodegeneration 

      Bhat, Vadiraja B.; Seneviratne, Uthpala Indrajith; Nott, Alexander; Kodihalli, Ravindra; Wishnok, John S; e.a. (National Academy of Sciences (U.S.), 2016-04)
      Protein S-nitrosation (SNO-protein), the nitric oxide-mediated posttranslational modification of cysteine thiols, is an important regulatory mechanism of protein function in both physiological and pathological pathways. A ...
    • S-nitrosylation of E3 ubiquitin-protein ligase RNF213 alters non-canonical Wnt/Ca+2 signaling in the P301S mouse model of tauopathy 

      Amal, Haitham; Gong, Guanyu; Gjoneska, Elizabeta; Lewis, Sarah M; Wishnok, John S.; e.a. (Springer Nature, 2019-01)
      Mutations in the MAPT gene, which encodes the tau protein, are associated with several neurodegenerative diseases, including frontotemporal dementia (FTD), dementia with epilepsy, and other types of dementia. The missense ...
    • S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson’s Disease Models 

      Oh, Chang-Ki; Sultan, Abdullah; Platzer, Joseph; Dolatabadi, Nima; Soldner, Frank; e.a. (Elsevier, 2017-11)
      Mutations in PARK6 (PINK1) and PARK2 (Parkin) are linked to rare familial cases of Parkinson's disease (PD). Mutations in these genes result in pathological dysregulation of mitophagy, contributing to neurodegeneration. ...
    • S-Store: a streaming NewSQL system for big velocity applications 

      Cetintemel, Ugur; Tufte, Kristin; Wang, Hao; Zdonik, Stanley; Du, Jiang; e.a. (Association for Computing Machinery (ACM), 2014-08)
      First-generation streaming systems did not pay much attention to state management via ACID transactions (e.g., [3, 4]). S-Store is a data management system that combines OLTP transactions with stream processing. To create ...
    • S-Store: streaming meets transaction processing 

      Meehan, John; Pavlo, Andrew; Tufte, Kristin; Zdonik, Stan; Aslantas, Cansu; e.a. (Association for Computing Machinery, 2015-09)
      Stream processing addresses the needs of real-time applications. Transaction processing addresses the coordination and safety of short atomic computations. Heretofore, these two modes of operation existed in separate, ...
    • S2ADC: A 12-bit, 1.25MS/s Secure SAR ADC with Power Side-Channel Attack Resistance 

      Jeong, Taehoon; Chandrakasan, Anantha P; Lee, Hae-Seung (Institute of Electrical and Electronics Engineers (IEEE), 2020-04)
      This paper presents a neural-network-based SAR ADC power side-channel attack (PSA) method and a 12-bit, 1.25MS/s secure SAR ADC whose current equalizers protect the ADC from PSA. A prototype SAR ADC was fabricated in 65nm ...
    • S[subscript n]-equivariant sheaves and Koszul cohomology 

      Yang, David H. (Springer, 2014-11)
      Purpose: We give a new interpretation of Koszul cohomology, which is equivalent under the Bridgeland-King-Reid equivalence to Voisin's Hilbert scheme interpretation in dimensions 1 and 2 but is different in higher ...
    • Sacred Cars? Cost-Effective Regulation of Stationary and Nonstationary Pollution Sources 

      Fowlie, Meredith; Knittel, Christopher Roland; Wolfram, Catherine (American Economic Association, 2012-02)
      For political and practical reasons, environmental regulations sometimes treat point-source polluters, such as power plants, differently from mobile-source polluters, such as vehicles. This paper measures the extent of ...
    • Sacrificial-Post Templating Method for Block Copolymer Self-Assembly 

      Alexander-Katz, Alfredo; Ross, Caroline A.; Berggren, Karl K.; Tavakkoli Kermani Ghariehali, Amir; Nicaise, Sam; e.a. (Wiley Blackwell, 2013-07)
      A sacrificial-post templating method is presented for directing block copolymer self-assembly to form nanostructures consisting of monolayers and bilayers of microdomains. In this approach, the topographical post template ...
    • Saddle Point in the Minimax Converse for Channel Coding 

      Polyanskiy, Yury (Institute of Electrical and Electronics Engineers, 2013-05)
      A minimax metaconverse has recently been proposed as a simultaneous generalization of a number of classical results and a tool for the nonasymptotic analysis. In this paper, it is shown that the order of optimizing the ...
    • Saddle point localization of molecular wavefunctions 

      Mellau, Georg Ch.; Kyuberis, Alexandra A.; Polyansky, Oleg L.; Zobov, Nikolai; Field, Robert W (Nature Publishing Group, 2016-09)
      The quantum mechanical description of isomerization is based on bound eigenstates of the molecular potential energy surface. For the near-minimum regions there is a textbook-based relationship between the potential and ...
    • Safe and efficient high dimensional motion planning in space-time with time parameterized prediction 

      Li, Shen; Shah, Julie A (IEEE, 2019)
      In this work, we propose an algorithm that can plan safe and efficient robot trajectories in real time, given time-parameterized motion predictions, in order to avoid fast-moving obstacles in human-robot collaborative ...
    • Safe and Efficient Tetrazole Synthesis in a Continuous Flow Microreactor 

      Palde, Prakash B.; Jamison, Timothy F. (Wiley Blackwell, 2011-03)
      Safer flow: The synthesis of 5-substituted tetrazoles in flow (see scheme) is safe, efficient, scalable, requires no metal promoter, and uses a near-equimolar amount of NaN[subscript 3], yet nonetheless displays a broad ...
    • Safe Asset Scarcity and Aggregate Demand 

      Farhi, Emmanuel; Gourinchas, Pierre-Olivier; Caballero, Ricardo J (American Economic Association, 2016-05)
      We explore the consequences of safe asset scarcity on aggregate demand in a stylized IS-LM/Mundell Fleming style environment. Acute safe asset scarcity forces the economy into a "safety trap" recession. In the open economy, ...
    • The Safe Assets Shortage Conundrum 

      Farhi, Emmanuel; Gourinchas, Pierre-Olivier; Caballero, Ricardo J (American Economic Association, 2017-08)
      A safe asset is a simple debt instrument that is expected to preserve its value during adverse systemic events. The supply of safe assets, private and public, has historically been concentrated in a small number of advanced ...
    • Safe Fall: Humanoid robot fall direction change through intelligent stepping and inertia shaping 

      Yun, Seung-kook; Goswami, Ambarish; Sakagami, Yoshiaki (Institute of Electrical and Electronics Engineers (IEEE), 2009-08)
      Although fall is a rare event in the life of a humanoid robot, we must be prepared for it because its consequences are serious. In this paper we present a fall strategy which rapidly modifies the robot's fall direction in ...
    • Safe Local Navigation for Visually Impaired Users with a Time-of-Flight and Haptic Feedback Device 

      Katzschmann, Robert Kevin; Araki, Brandon; Rus, Daniela L (Institute of Electrical and Electronics Engineers (IEEE), 2018-03)
      This paper presents ALVU (Array of Lidars and Vibrotactile Units), a contactless, intuitive, hands-free, and discreet wearable device that allows visually impaired users to detect low- and high-hanging obstacles, as well ...
    • Safe Local Navigation for Visually Impaired Users With a Time-of-Flight and Haptic Feedback Device 

      Katzschmann, Robert Kevin; Rus, Daniela L; Araki, Minoru B (Institute of Electrical and Electronics Engineers (IEEE), 2018-01)
      This paper presents ALVU (Array of Lidars and Vibrotactile Units), a contactless, intuitive, hands-free, and discreet wearable device that allows visually impaired users to detect low- and high-hanging obstacles, as well ...
    • Safe Reinforcement Learning With Model Uncertainty Estimates 

      Lutjens, Bjorn; Everett, Michael F; How, Jonathan P (IEEE, 2019-08)
      Many current autonomous systems are being designed with a strong reliance on black box predictions from deep neural networks (DNNs). However, DNNs tend to be overconfident in predictions on unseen data and can give ...