Browsing MIT Open Access Articles by Title
Now showing items 16986-17005 of 55760
-
Extracellular Matrix Heterogeneity Regulates Three-Dimensional Morphologies of Breast Adenocarcinoma Cell Invasion
(Wiley Blackwell, 2012-11)Plasticity and reciprocity of breast cancer cells to various extracellular matrice (ECMs) are three-dimensionally analyzed in quantitative way in a novel and powerful microfluidic in vitro platform. This successfully ... -
Extracellular matrix remodelling induced by alternating electrical and mechanical stimulations increases the contraction of engineered skeletal muscle tissues
(Springer Nature, 2019-02)Engineered skeletal muscles are inferior to natural muscles in terms of contractile force, hampering their potential use in practical applications. One major limitation is that the extracellular matrix (ECM) not only impedes ... -
Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters
(eLife Sciences Publications, Ltd., 2014-03)The extracellular matrix (ECM) is a major component of tumors and a significant contributor to cancer progression. In this study, we use proteomics to investigate the ECM of human mammary carcinoma xenografts and show that ... -
Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver
(BioMed Central Ltd., 2014-07)Background: Colorectal cancer is the third most frequently diagnosed cancer and the third cause of cancer deaths in the United States. Despite the fact that tumor cell-intrinsic mechanisms controlling colorectal carcinogenesis ... -
The Extracellular Matrix: Not Just Pretty Fibrils
(American Association for the Advancement of Science (AAAS), 2009-11)The extracellular matrix (ECM) and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases. The ECM has many effects beyond providing structural support. ... -
The extracellular matrix: Tools and insights for the “omics” era
(Elsevier, 2015-06)The extracellular matrix (ECM) is a fundamental component of multicellular organisms that provides mechanical and chemical cues that orchestrate cellular and tissue organization and functions. Degradation, hyperproduction ... -
Extracellular Reef Metabolites Across the Protected Jardines de la Reina, Cuba Reef System
(Frontiers Media SA, 2020-12)Coral reef ecosystems are incredibly diverse marine biomes that rely on nutrient cycling by microorganisms to sustain high productivity in generally oligotrophic regions of the ocean. Understanding the composition of ... -
Extracellular Spike Waveform Dissociates Four Functionally Distinct Cell Classes in Primate Cortex
(Elsevier BV, 2019)© 2019 Elsevier Ltd Trainito et al. use a data-driven approach to robustly identify four cell classes from extracellular spike waveforms recorded in three cortical regions of macaque monkeys. The four cell classes are ... -
Extracellular vesicle-carried Jagged-1 inhibits HUVEC sprouting in a 3D microenvironment
(Springer Netherlands, 2018-03-14)Abstract NOTCH signalling is an evolutionarily conserved juxtacrine signalling pathway that is essential in development. Jagged1 (JAG1) and Delta-like ligand 4 (DLL4) are transmembrane NOTCH ligands that ... -
Extracorporeal Membrane Oxygenation Resource Planning in the Setting of Pandemic Respiratory Illness
(American Thoracic Society, 2020-07) -
EXTRACT: Strong Examples from Weakly-Labeled Sensor Data
(IEEE, 2016-12)© 2016 IEEE. Thanks to the rise of wearable and connected devices, sensor-generated time series comprise a large and growing fraction of the world's data. Unfortunately, extracting value from this data can be challenging, ... -
Extracting a short distance top mass with light grooming
(American Physical Society (APS), 2019)© 2019 authors. Published by the American Physical Society. We propose a kinematic method based on a factorization formula for precisely measuring the top quark mass mt in pp collisions using boosted top jets with light ... -
Extracting and Optimizing Formally Verified Code for Systems Programming
(Springer International Publishing, 2019-05)MCQC is a compiler for extracting verified systems programs to low-level assembly, with no runtime or garbage collection requirements and an emphasis on performance. MCQC targets the Gallina functional language used in the ... -
Extracting aspects of determiner meaning from dialogue in a virtual world environment
(Association for Computing Machinery, 2011-01)We use data from a virtual world game for automated learning of words and grammatical constructions and their meanings. The language data are an integral part of the social interaction in the game and consist of chat ... -
Extracting commuting patterns in railway networks through matrix decompositions
(Institute of Electrical and Electronics Engineers (IEEE), 2014-12)With the rise in the population of the world's cities, understanding the dynamics of commuters' transportation patterns has become crucial in the planning and management of urban facilities and services. In this study, we ... -
Extracting Design Principles for Efficient Thermally Activated Delayed Fluorescence (TADF) from a Simple Four-State Model
(American Chemical Society (ACS), 2019-06)We introduce a simple quantum-mechanical model for thermally activated delayed fluorescence (TADF). The Hamiltonian is represented in the basis of four spin-mixed diabatic states representing pure charge transfer (CT) and ... -
Extracting film thickness and optical constants from spectrophotometric data by evolutionary optimization
(Public Library of Science (PLoS), 2022)<jats:p>In this paper, we propose a simple and elegant method to extract the thickness and the optical constants of various films from the reflectance and transmittance spectra in the wavelength range of 350 − 1000 nm. The ... -
Extracting functional requirements from design documentation using machine learning
(Elsevier BV, 2021)Good design practice and digital tools have enabled industry to produce valuable products. Early-stage design research involves rigorous background study of large volumes of design documentation which designers must analyze ... -
Extracting functional requirements from design documentation using machine learning
(Elsevier BV, 2021-06)Good design practice and digital tools have enabled industry to produce valuable products. Early-stage design research involves rigorous background study of large volumes of design documentation which designers must analyze ... -
Extracting Gait Velocity and Stride Length from Surrounding Radio Signals
(ACM, 2017-05-02)© 2017 ACM. Gait velocity and stride length are critical health indicators for older adults. A decade of medical research shows that they provide a predictor of future falls, hospitalization, and functional decline among ...