Now showing items 17400-17419 of 51589

    • Function approximation by deep networks 

      Mhaskar, H. N.; Poggio, Tomaso A (American Institute of Mathematical Sciences (AIMS), 2020-08-01)
      © 2020 American Institute of Mathematical Sciences. All rights reserved. We show that deep networks are better than shallow networks at approximating functions that can be expressed as a composition of functions described ...
    • Function approximation by deep networks 

      Mhaskar, HN; Poggio, T (American Institute of Mathematical Sciences (AIMS), 2020-08-01)
      © 2020 American Institute of Mathematical Sciences. All rights reserved. We show that deep networks are better than shallow networks at approximating functions that can be expressed as a composition of functions described ...
    • Function Based Design-by-Analogy: A Functional Vector Approach to Analogical Search 

      Murphy, Jeremy; Otto, Kevin; Jensen, Dan; Wood, Kristin; Fu, Katherine K; e.a. (ASME International, 2014-08)
      Design-by-analogy is a powerful approach to augment traditional concept generation methods by expanding the set of generated ideas using similarity relationships from solutions to analogous problems. While the concept of ...
    • Function Load Balancing over Networks 

      Malak, Derya; Medard, Muriel (Institute of Electrical and Electronics Engineers (IEEE), 2021)
    • Function of Drosophila Synaptotagmins in membrane trafficking at synapses 

      Quiñones-Frías, Mónica C.; Littleton, J. T. (Springer International Publishing, 2021-02-22)
      Abstract The Synaptotagmin (SYT) family of proteins play key roles in regulating membrane trafficking at neuronal synapses. Using both Ca2+-dependent and Ca2+-independent interactions, several SYT isoforms ...
    • Function of Drosophila Synaptotagmins in membrane trafficking at synapses 

      Quiñones-Frías, Mónica C.; Littleton, J. T. (Springer International Publishing, 2021-02-22)
      Abstract The Synaptotagmin (SYT) family of proteins play key roles in regulating membrane trafficking at neuronal synapses. Using both Ca2+-dependent and Ca2+-independent interactions, several SYT isoforms ...
    • Function of the Diiron Cluster of Escherichia coli Class Ia Ribonucleotide Reductase in Proton-Coupled Electron Transfer 

      Wörsdörfer, Bigna; Conner, Denise A.; Yokoyama, Kenichi; Livada, Jovan; Jiang, Wei; e.a. (American Chemical Society (ACS), 2013-05)
      The class Ia ribonucleotide reductase (RNR) from Escherichia coli employs a free-radical mechanism, which involves bidirectional translocation of a radical equivalent or “hole” over a distance of ~35 Å from the stable ...
    • Function-based Intersubject Alignment of Human Cortical Anatomy 

      Sabuncu, Mert R.; Singer, Benjamin D.; Conroy, Bryan,; Bryan, Ronald E.; Ramadge, Peter J.; e.a. (Oxford University Press, 2009-05)
      Making conclusions about the functional neuroanatomical organization of the human brain requires methods for relating the functional anatomy of an individual's brain to population variability. We have developed a method ...
    • Functional Alterations in Cerebellar Functional Connectivity in Anxiety Disorders 

      Lee, Yoon Ji; Guell, Xavier; Hubbard, Nicholas; Siless, Viviana; Frosch, Isabelle; e.a. (Springer Science and Business Media LLC, 2020-11)
      Adolescents with anxiety disorders exhibit excessive emotional and somatic arousal. Neuroimaging studies have shown abnormal cerebral cortical activation and connectivity in this patient population. The specific role of ...
    • Functional analysis of CX3CR1 in human induced pluripotent stem (iPS) cell‐derived microglia‐like cells 

      Murai, Nobuhito; Mitalipova, Maisam; Jaenisch, Rudolf (Wiley, 2020)
      © 2020 Federation of European Neuroscience Societies and John Wiley & Sons Ltd Microglia are the primary immune cells of the central nervous system and crucial to proper development and maintenance of the brain. Microglia ...
    • Functional anatomy of neural circuits regulating fear and extinction 

      Sheng, Morgan Hwa-Tze; Knapska, Ewelina; Macias, Matylda; Mikosz, Marta; Nowak, Aleksandra; e.a. (National Academy of Sciences (U.S.), 2012-10)
      The memory of fear extinction is context dependent: fear that is suppressed in one context readily renews in another. Understanding of the underlying neuronal circuits is, therefore, of considerable clinical relevance for ...
    • Functional and Computational Genomics Reveal Unprecedented Flexibility in Stage-Specific Toxoplasma Metabolism 

      Krishnan, Aarti; Kloehn, Joachim; Lunghi, Matteo; Chiappino-Pepe, Anush; Waldman, Benjamin S; e.a. (Elsevier BV, 2020)
      © 2020 Elsevier Inc. To survive and proliferate in diverse host environments with varying nutrient availability, the obligate intracellular parasite Toxoplasma gondii reprograms its metabolism. We have generated and curated ...
    • Functional and shunt states of bacteriorhodopsin resolved by 250 GHz dynamic nuclear polarization-enhanced solid-state NMR 

      Bajaj, Vikram S.; Mak-Jurkauskas, Melody L.; Belenky, Marina; Herzfeld, Judith; Griffin, Robert Guy (National Academy of Sciences, 2009-06)
      Observation and structural studies of reaction intermediates of proteins are challenging because of the mixtures of states usually present at low concentrations. Here, we use a 250 GHz gyrotron (cyclotron resonance maser) ...
    • Functional and structural brain correlates of risk for major depression in children with familial depression 

      Hirshfeld-Becker, Dina; Biederman, Joseph; Uchida, Mai; Doehrmann, Oliver; Kenworthy, Tara; e.a. (Elsevier, 2015-05)
      Despite growing evidence for atypical amygdala function and structure in major depression, it remains uncertain as to whether these brain differences reflect the clinical state of depression or neurobiological traits that ...
    • Functional and topological diversity of LOV domain photoreceptors 

      Glantz, Spencer T.; Carpenter, Eric J.; Melkonian, Michael; Gardner, Kevin H.; Wong, Gane Ka-Shu; e.a. (National Academy of Sciences (U.S.), 2016-02)
      Light–oxygen–voltage sensitive (LOV) flavoproteins are ubiquitous photoreceptors that mediate responses to environmental cues. Photosensory inputs are transduced into signaling outputs via structural rearrangements in ...
    • Functional Architecture for Disparity in Macaque Inferior Temporal Cortex and Its Relationship to the Architecture for Faces, Color, Scenes, and Visual Field 

      Verhoef, Bram-Ernst; Bohon, Kaitlin S.; Conway, Bevil (Society for Neuroscience, 2015-04)
      Binocular disparity is a powerful depth cue for object perception. The computations for object vision culminate in inferior temporal cortex (IT), but the functional organization for disparity in IT is unknown. Here we ...
    • Functional Association of Gdown1 with RNA Polymerase II Poised on Human Genes 

      Cheng, Bo; Li, Tiandao; Rahl, Peter B.; Adamson, Todd E.; Loudas, Nicholas B.; e.a. (Elsevier, 2012-01)
      Most human genes are loaded with promoter-proximally paused RNA polymerase II (Pol II) molecules that are poised for release into productive elongation by P-TEFb. We present evidence that Gdown1, the product of the POLR2M ...
    • Functional Biases in Visual Cortex Neurons with Identified Projections to Higher Cortical Targets 

      Jarosiewicz, Beata; Schummers, James; Malik, Wasim Qamar; Brown, Emery N.; Sur, Mriganka (Elsevier, 2012-02)
      Background: Visual perception involves information flow from lower- to higher-order cortical areas, which are known to process different kinds of information. How does this functional specialization arise? As a step toward ...
    • Functional Brain Basis of Hypnotizability 

      Hoeft, Fumiko; Haas, Brian W.; Bammer, Roland; Menon, Vinod; Spiegel, David; e.a. (American Medical Association, 2012-10)
      Context Focused hypnotic concentration is a model for brain control over sensation and behavior. Pain and anxiety can be effectively alleviated by hypnotic suggestion, which modulates activity in brain regions associated ...
    • Functional characterization of bacterial sRNAs using a network biology approach 

      Walker, Graham C.; Modia, Sheetal R.; Camacho, Diogo M.; Kohanski, Michael A.; Collins, James J. (Proceedings of the National Academy of Sciences (PNAS), 2011-08)
      Small RNAs (sRNAs) are important components of posttranscriptional regulation. These molecules are prevalent in bacterial and eukaryotic organisms, and involved in a variety of responses to environmental stresses. The ...