Browsing MIT Open Access Articles by Author "Kaas, Christian S."
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A CRISPR–Cas9-based gene drive platform for genetic interaction analysis in Candida albicans
Shapiro, Rebecca S.; Chavez, Alejandro; Porter, Caroline B. M.; Hamblin, Meagan; Kaas, Christian S.; e.a. (Nature Publishing Group, 2017-10)Candida albicans is the leading cause of fungal infections; yet, complex genetic interaction analysis remains cumbersome in this diploid pathogen. Here, we developed a CRISPR-Cas9-based 'gene drive array' platform to ...