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Browsing MIT Open Access Articles by Title

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  • Davidson, Robert M.; Seneff, Stephanie (MDPI AG, 2012-08)
    In reviewing the literature pertaining to interfacial water, colloidal stability, and cell membrane function, we are led to propose that a cascade of events that begins with acute exogenous surfactant-induced interfacial ...
  • Lander, Eric S.; Chapman, Michael A.; Lawrence, Michael S.; Keats, Jonathan J.; Cibulskis, Kristian; Sougnez, Carrie; Schinzel, Anna C.; Harview, Christina L.; Brunet, Jean-Philippe; Ahmann, Gregory J.; Adli, Mazhar; Anderson, Kenneth C.; Ardlie, Kristin; Auclair, Daniel; Baker, Angela; Bergsagel, P. Leif; Bernstein, Bradley E.; Drier, Yotam; Fonseca, Rafael; Gabriel, Stacey B. (Nature Publishing Group, 2011-03)
    Multiple myeloma is an incurable malignancy of plasma cells, and its pathogenesis is poorly understood. Here we report the massively parallel sequencing of 38 tumour genomes and their comparison to matched normal DNAs. ...
  • Labelle, Myriam; Hynes, Richard O. (American Association for Cancer Research, 2012-11)
    Tumor cells transit from the primary tumor via the blood circulation to form metastases in distant organs. During this process, tumor cells encounter a number of environmental challenges and stimuli that profoundly impact ...
  • Blanchard, Olivier Jean; Das, Mitali; Faruqee, Hamid (Brookings Institution Press, 2010-06)
    To understand the diverse impact of the crisis across emerging market countries, we explore the role of two shocks—the collapse in trade and the sharp decline in financial flows—in the transmission of the crisis from ...
  • Massachusetts Institute of Technology. Department of Biology; Broad Institute of MIT and Harvard; Lander, Eric S.; Lander, Eric S. (Nature Publishing Group, 2011-02)
    The sequence of the human genome has dramatically accelerated biomedical research. Here I explore its impact, in the decade since its publication, on our understanding of the biological functions encoded in the genome, on ...
  • Kaur, Gurneet; Cappellaro, Paola (IOP Publishing, 2012-08)
    Linear chains of spins acting as quantum wires are a promising approach for achieving scalable quantum information processors. Nuclear spins in apatite crystals provide an ideal test bed for the experimental study of quantum ...
  • Da Rio, N.; Robberto, M.; Hillenbrand, L. A.; Henning, T.; Stassun, Keivan (Institute of Physics/American Astronomical Society, 2012-03)
    We present a new census of the Orion Nebula Cluster over a large field of view (gsim 30' × 30'), significantly increasing the known population of stellar and substellar cluster members with precisely determined properties. ...
  • Andrews, J. E.; Calzetti, D.; Chandar, R.; Lee, J. C.; Elmegreen, B. G.; Kennicutt, R. C.; Whitmore, B.; Kissel, Jeffrey S.; da Silva, Robert L.; Krumholz, Mark R.; O'Connell, R. W.; Dopita, M. A.; Frogel, Jay A.; Kim, Hwihyun (Institute of Physics/American Astronomical Society, 2013-04)
    The production rate of ionizing photons in young (≤8 Myr), unresolved stellar clusters in the nearby irregular galaxy NGC 4214 is probed using multi-wavelength Hubble Space Telescope WFC3 data. We normalize the ionizing ...
  • Smith, David Edmund; Zuber, Maria; Neumann, Gregory A.; Lemoine, Frank G.; Mazarico, Erwan Matias; Torrence, Mark H.; McGarry, Jan F.; Rowlands, David D.; Head, James W.; Duxbury, Thomas H.; Aharonson, Oded; Lucey, Paul G.; Robinson, Mark S.; Barnouin, Olivier S.; Cavanaugh, John F.; Sun, Xiaoli; Liiva, Peter; Mao, Dandan; Smith, James C.; Bartels, Arlin E. (American Geophysical Union, 2010-09)
    As of June 19, 2010, the Lunar Orbiter Laser Altimeter, an instrument on the Lunar Reconnaissance Orbiter, has collected over 2.0 × 109 measurements of elevation that collectively represent the highest resolution global ...
  • Adhikari, G.; Adhikari, P.; de Souza, E. B; Carlin, N.; Choi, S.; Choi, W. Q; Djamal, M.; Ezeribe, A. C; Ha, C.; Hahn, I. S; Hubbard, A. J F; Jeon, E. J; Jo, J. H; Joo, H. W; Kang, W. G; Kang, W.; Kauer, M.; Kim, B. H; Kim, H.; Kim, H. J; Kim, K. W; Kim, M. C; Kim, N. Y; Kim, S. K; Kim, Y. D; Kim, Y. H; Kudryavtsev, V. A; Lee, H. S; Lee, J.; Lee, J. Y; Lee, M. H; Leonard, D. S; Lim, K. E; Lynch, W. A; Maruyama, R. H; Mouton, F.; Olsen, S. L; Park, H. K; Park, H. S; Park, J. S; Park, K. S; Pettus, W.; Pierpoint, Z. P; Prihtiadi, H.; Ra, S.; Rott, C.; Scarff, A.; Spooner, N. J C; Thompson, W. G; Yang, L.; Yong, S. H; Rogers, Field Rose (Springer-Verlag, 2018-02)
    COSINE is a dark matter search experiment based on an array of low background NaI(Tl) crystals located at the Yangyang underground laboratory. The assembly of COSINE-100 was completed in the summer of 2016 and the detector ...
  • Carlin, N.; de Souza, E. Barbosa; Adhikari, P.; Adhikari, G.; Yong, S. H.; Yang, L.; Thompson, W. G.; Spooner, N. J. C.; Scarff, A.; Rott, C.; Ra, S.; Prihtiadi, H.; Pierpoint, Z. P.; Pettus, W.; Park, K. S.; Park, J. S.; Park, H. S.; Park, H. K.; Olsen, S. L.; Mouton, F.; Maruyama, R. H.; Lynch, W. A.; Lim, K. E.; Leonard, D. S.; Lee, M. H.; Lee, J. Y.; Lee, J.; Lee, H. S.; Kudryavtsev, V. A.; Kim, Y. H.; Kim, Y. D.; Kim, S. K.; Kim, N. Y.; Kim, M. C.; Kim, K. W.; Kim, H. J.; Kim, H.; Kim, B. H.; Kauer, M.; Kang, W.; Kang, W. G.; Joo, H. W.; Jo, J. H.; Jeon, E. J.; Hubbard, A. J. F.; Hahn, I. S.; Ha, C.; Ezeribe, A. C.; Djamal, M.; Choi, W. Q.; Choi, S.; Rogers, Field Rose (Springer/Società Italiana di Fisica, 2018-02)
    COSINE is a dark matter search experiment based on an array of low background NaI(Tl) crystals located at the Yangyang underground laboratory. The assembly of COSINE-100 was completed in the summer of 2016 and the detector ...
  • Burgess, S. D.; Muirhead, J. D.; Bowring, Samuel A (Nature Publishing Group, 2017-07)
    Mass extinction events are short-lived and characterized by catastrophic biosphere collapse and subsequent reorganization. Their abrupt nature necessitates a similarly short-lived trigger, and large igneous province magmatism ...
  • Gates, Jonathan D.; Arabian, Sandra; Biddinger, Paul; Blansfield, Joe; Burke, Peter; Chung, Sarita; Friedman, Franklin; Gervasini, Alice; Goralnick, Eric; Gupta, Alok; Larentzakis, Andreas; McMahon, Maria; Mella, Juan; Michaud, Yvonne; Rabinovici, Reuven; Sweet, Darlene; Ulrich, Andrew; Velmahos, George; Weber, Cheryl; Fischer, Jonathan D; Yaffe, Michael B (Ovid Technologies (Wolters Kluwer Health), 2017-07)
    We discuss the strengths of the medical response to the Boston Marathon bombings that led to the excellent outcomes. Potential shortcomings were recognized, and lessons learned will provide a foundation for further ...
  • ODay, Buckley Earl; Hartwig, Zachary Seth; Lanza, Richard C; Danagoulian, Areg (Elsevier BV, 2016-05)
    The detection of assembled nuclear devices and concealed special nuclear materials (SNM) such as plutonium or uranium in commercial cargo traffic is a major challenge in mitigating the threat of nuclear terrorism. Currently ...
  • Hartwig, Z. S.; Wright, G. M.; Kesler, Leigh Ann; Sorbom, Brandon Nils; Barnard, Harold Salvadore; Whyte, Dennis G (Elsevier, 2016-12)
    The Accelerator-Based In Situ Materials Surveillance (AIMS) diagnostic was developed to perform in situ ion beam analysis (IBA) on Alcator C-Mod in August 2012 to study divertor surfaces between shots. These results were ...
  • Cowan, Ray Franklin; Dujmic, Denis; Sciolla, Gabriella (American Physical Society, 2012-06)
    We study the process e[superscript +] e-→π[superscript +]π[superscript -]π[superscript +] π[superscript -], with a photon emitted from the initial-state electron or positron, using 454.3  fb-1 of data collected with the ...
  • Cerrillo, Javier; Schaller, Gernot; Buser, Maximilian; Cao, Jianshu (American Physical Society, 2017-12)
    Open quantum systems exhibiting initial system-environment correlations are notoriously difficult to simulate. We point out that given a sufficiently long sample of the exact short-time evolution of the open system dynamics, ...
  • Gaya, Mauro; Barral, Patricia; Burbage, Marianne; Aggarwal, Shweta; Montaner, Beatriz; Warren Navia, Andrew; Aid, Malika; Tsui, Carlson; Maldonado, Paula; Nair, Usha; Ghneim, Khader; Fallon, Padraic G.; Sekaly, Rafick-Pierre; Barouch, Dan H.; Bruckbauer, Andreas; Strid, Jessica; Batista, Facundo D.; Shalek, Alexander K (Elsevier, 2017-12)
    B cells constitute an essential line of defense from pathogenic infections through the generation of class-switched antibody-secreting cells (ASCs) in germinal centers. Although this process is known to be regulated by ...
  • Dong, Yizhou; Xue, Kun; Weir, Gordon C.; Wang, Weiheng; Veiseh, Omid; Appel, Eric; Webber, Matthew; Tang, Benjamin C.; Yang, Xiwen; Langer, Robert S; Anderson, Daniel Griffith (American Chemical Society (ACS), 2016-07)
    Injectable hydrogels have been widely used for a number of biomedical applications. Here, we report a new strategy to form an injectable and glucose-responsive hydrogel using the boronic acid–glucose complexation. The ratio ...
  • Kohane, Daniel S.; Fink, Gerald R.; Langer, Robert; Hudson, Sarah (Elsevier, 2009-11)
    Invasive fungal infections can be devastating, particularly in immunocompromised patients, and difficult to treat with systemic drugs. Furthermore, systemic administration of those medications can have severe side effects. ...
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