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Browsing MIT Open Access Articles by Title

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  • Kessler, Sean Herbert; Daumit, Kelly Elizabeth; Kroll, Jesse (Royal Society of Chemistry, 2013-05)
    Measurements of ambient organic aerosol indicate that a substantial fraction is highly oxidized and low in volatility, but this fraction is generally not reproduced well in either laboratory studies or models. Here we ...
  • Tsitsiklis, John N. (Institute of Electrical and Electronics Engineers (IEEE), 2011-06)
    In distributed consensus and averaging algorithms, processors exchange and update certain values ("estimates" or "opinions") by forming a local average with the values of their neighbors. Under suitable conditions, such ...
  • Martin, Ian W. R.; Pindyck, Robert S (American Economic Association, 2015-10)
    Faced with numerous potential catastrophes--nuclear and bioterrorism, mega-viruses, climate change, and others--which should society attempt to avert? A policy to avert one catastrophe considered in isolation might be ...
  • Jiang, Taijiao; Keating, Amy E. (BioMed Central Ltd, 2005-06)
    Background: Determining the functions of uncharacterized proteins is one of the most pressing problems in the post-genomic era. Large scale protein-protein interaction assays, global mRNA expression analyses and systematic ...
  • Bajpayee, Ambika G.; Wong, Cliff R.; Bawendi, Moungi G.; Grodzinsky, Alan J.; Frank, Eliot (Elsevier, 2013-10)
    Local drug delivery into cartilage remains a challenge due to its dense extracellular matrix of negatively charged proteoglycans enmeshed within a collagen fibril network. The high negative fixed charge density of cartilage ...
  • Ponda, Sameera S.; Huber, Olivier; Choi, Han-Lim; How, Jonathan P. (Institute of Electrical and Electronics Engineers, 2011-01)
    This paper proposes an extension to the Consensus-Based Bundle Algorithm (CBBA), a distributed task allocation framework previously developed at the Aerospace Control Laboratory (ACL), MIT, designed to address complex ...
  • Taylor, Justin Q.; Kovacik, Peter; Traer, James A.; Zakahi, Philip Javier; Oslowski, Christine; Widge, Alik; Glorioso, Christin A. (eLife Sciences Publications, Ltd., 2016-05)
    By sharing their experiences, early-career scientists can help to make the case for increased government funding for researchers.
  • Parandehgheibi, Ail; Medard, Muriel; Shakkottai, Srinivas; Ozdaglar, Asuman E. (Institute of Electrical and Electronics Engineers, 2010-07)
    We take an analytical approach to study Quality of user Experience (QoE) for media streaming applications. We use the fact that random linear network coding applied to blocks of video frames can significantly simplify the ...
  • Akeju, Oluwaseun; Brown, Emery N. (eLife Sciences Publications, Ltd., 2013-11)
    Characteristic changes in brain activity accompany the paradoxical increase in alertness observed in some patients with severe brain injury when they are treated with the sleeping pill zolpidem.
  • Gamble, Carly; Colas, Pierre; Guen, Vincent; Lees, Jacqueline (Impact Journals/National Center for Biotechnology Information (U.S.), 2017-02)
    Cyclin-dependent kinases (CDKs) play important roles in the control of fundamental cellular processes. Some of the most characterized CDKs are considered to be pertinent therapeutic targets for cancers and other diseases, ...
  • Axel 
    Abad-Manterola, Pablo; Edlund, Jeffrey A.; Burdick, Joel W.; Wu, Albert; Oliver, Thomas; Nesnas, Issa A. D.; Cecava, Johanna (Institute of Electrical and Electronics Engineers, 2009-12)
    Recent scientific findings suggest that some of the most interesting sites for future exploration of planetary surfaces lie in terrains that are currently inaccessible to conventional robotic rovers. To provide robust and ...
  • Nordlund, Mats; Lee, Taesik; Kim, Sang-Gook (ASME International, 2015-11)
    In 1977, Nam P Suh proposed a different approach to design research. Suh’s approach was different in that it introduced the notions of domains and layers in a 2-D design thinking and stipulated a set of axioms that describes ...
  • Nordlund, Mats; Kim, Sang-Gook; Tate, Derrick E.; Lee, Taesik; Oh, Hilario L (Elesvier, 2016-08)
    Design broadly defined deals with mapping from societal wants or needs to means for satisfying these needs. Axiomatic design is a well-known approach to design that was initially proposed by Nam P. Suh in the late 1970s. ...
  • Phadnis, Shardul; Caplice, Christopher; Singh, Mahender; Sheffi, Yosef (Elsevier, 2014-07)
    This paper presents an axiomatic foundation for developing firm-specific scenarios in the tradition of the Intuitive Logics School (ILS), a structured scenario creation process built on that foundation, and its application ...
  • Krasheninnikov, S. I.; Catto, Peter J (Pleiades Publishing, 2015-12)
    Plasma equilibria in gravitational and open-ended magnetic fields are considered for the case of topologically disconnected regions of the magnetic flux surfaces where plasma occupies just one of these regions. Special ...
  • Meyer, Aaron Samuel; Zweemer, Jacomina M.; Lauffenburger, Douglas A (Elsevier, 2015-07)
    The AXL receptor is a TAM (Tyro3, AXL, MerTK) receptor tyrosine kinase (RTK) important in physiological inflammatory processes such as blood clotting, viral infection, and innate immune-mediated cell clearance. Overexpression ...
  • Rawson, Randi L.; Yam, Lung; Weimer, Robby M.; Bend, Eric G.; Horvitz, H. Robert; Clark, Scott G.; Jorgensen, Erik M.; Hartwieg, Erika A. (Elsevier, 2014-03)
    Many neurodegenerative disorders are associated with mitochondrial defects [1, 2 and 3]. Mitochondria can play an active role in degeneration by releasing reactive oxygen species and apoptotic factors [4, 5, 6 and 7]. ...
  • Kaertner, Franz X; Hobbs, Richard; Huang, W. R.; Nanni, Emilio Alessandro; Putnam, William P; Ravi, Koustuban; Berggren, Karl K (Elsevier, 2016-09)
    X-ray crystallography is one of the main methods to determine atomic-resolution 3D images of the whole spectrum of molecules ranging from small inorganic clusters to large protein complexes consisting of hundred-thousands ...
  • Ray, Paul S.; Chakrabarty, Deepto; Wilson-Hodge, Colleen A.; Philips, Bernard F.; Remillard, Ronald Alan; Levine, Alan M.; Wood, Kent S.; Wolff, Michael T.; Gwon, Chul S.; Strohmayer, Tod E.; Baysinger, Michael; Briggs, Michael S.; Capizzo, Peter; Fabisinski, Leo; Hopkins, Randall C.; Hornsby, Linda S.; Johnson, Les; Maples, C. Dauphne; Miernik, Janie H.; Thomas, Dan; de Geronimo, Gianluigi (SPIE, 2010-07)
    The Advanced X-ray Timing Array (AXTAR) is a mission concept for X-ray timing of compact objects that combines very large collecting area, broadband spectral coverage, high time resolution, highly flexible scheduling, and ...
  • Lee, Hyang-Yeol; Yerkes, Nancy Mary; O'Connor, Sarah Ellen; Yerkes, Nancy Mary (Elsevier B.V., 2009-12)
    Biosynthetic pathways can be hijacked to yield novel compounds by introduction of novel starting materials. Here we have altered tryptamine, which serves as the starting substrate for a variety of alkaloid biosynthetic ...
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