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Browsing MIT Open Access Articles by Title

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  • Sun, Hao Sheng; Maze, Ian; Dietz, David M.; Scobie, Kimberly N.; Kennedy, Pamela J.; Damez-Werno, Diane; Neve, Rachael L.; Zachario, Venetia; Shen, Li; Nestler, Eric J. (Society for Neuroscience, 2012-11)
    Dysregulation of histone modifying enzymes has been associated with numerous psychiatric disorders. Alterations in G9a (Ehmt2), a histone methyltransferase that catalyzes the euchromatic dimethylation of histone H3 at ...
  • Urban, Glen L.; MacDonald, Erin; Bordley, Robert; Hauser, John R.; Liberali, Guilherme (Institute for Operations Research and the Management Sciences (INFORMS), 2013-10)
    Researchers and practitioners devote substantial effort to targeting banner advertisements to consumers, but they focus less effort on how to communicate with consumers once targeted. Morphing enables a website to learn, ...
  • Dalbe, Marie Julie Elise; Juanes, Ruben (American Physical Society, 2018-02)
    We study experimentally the displacement of one fluid by another in a granular pack to uncover relationships between fluid invasion and medium deformation. We develop an experimental setup that allows us to reconstruct the ...
  • Quintana, Lluís; Nieden, Nicole I. zur; Semino, Carlos Eduardo (Mary Ann Liebert, 2008-12)
    Cartilage is the first skeletal tissue to be formed during embryogenesis leading to the creation of all mature cartilages and bones, with the exception of the flat bones in the skull. Therefore, errors occurring during ...
  • Wang, Zhengyuan; Du, Jianguo; Lam, Siew H.; Mathavan, Sinnakarupan; Matsudaira, Paul T.; Gong, Zhiyuan (BioMed Central Ltd., 2010-06)
    Background The zebrafish intestine is a simple tapered tube that is folded into three sections. However, whether the intestine is functionally similar along its length remains unknown. Thus, a systematic structural and ...
  • Kempes, Chris Poling; Okegbe, Chinweike; Mears-Clarke, Zwoisaint; Dietrich, Lars E. P.; Follows, Michael J. (National Academy of Sciences (U.S.), 2014-01)
    A major theme driving research in biology is the relationship between form and function. In particular, a longstanding goal has been to understand how the evolution of multicellularity conferred fitness advantages. Here ...
  • Petroff, Alexander Peter; Sim, Min Sub; Liang, Biqing; Bosak, Tanja (United States National Academy of Sciences, 2009-05)
    Conical stromatolites are thought to be robust indicators of the presence of photosynthetic and phototactic microbes in aquatic environments as early as 3.5 billion years ago. However, phototaxis alone cannot explain the ...
  • Narasimhan, Karthik Rajagopal; Karakos, Damianos; Schwartz, Richard; Tsakalidis, Stavros; Barzilay, Regina (2014-10)
    We explore the impact of morphological segmentation on keyword spotting (KWS). Despite potential benefits, state-of-the-art KWS systems do not use morphological information. In this paper, we augment a state-of-the-art KWS ...
  • Zhang, Liang; Demkowicz, Michael J. (American Institute of Physics (AIP), 2013-08)
    We use molecular dynamics and phase field simulations to demonstrate that Cu-Nb multilayered nanocomposites with individual layer thicknesses above 2–4 nm remain morphologically stable when subjected to 100 keV collision ...
  • Bidone, Tamara Carla; Jung, Wonyeong; Maruri, Daniel; Borau, Carlos; Kim, Taeyoon; Kamm, Roger Dale (Public Library of Science, 2017-01)
    Cells assemble numerous types of actomyosin bundles that generate contractile forces for biological processes, such as cytokinesis and cell migration. One example of contractile bundles is a transverse arc that forms via ...
  • González-Casanova, Diego F.; De Colle, Fabio; Ramirez-Ruiz, Enrico; Lopez, Laura A. (IOP Publishing, 2014-01)
    The circumstellar medium (CSM) of a massive star is modified by its winds before a supernova (SN) explosion occurs, and thus the evolution of the resulting supernova remnant (SNR) is influenced by both the geometry of the ...
  • Moffet, Ryan C.; Alpert, Peter A.; Kelly, Stephen T.; Pham, Don Q.; Gilles, Mary K.; Knopf, Daniel A.; Laskin, Alexander; Sellon, Rachel E. (Copernicus GmbH, 2016-11)
    Aerosol absorption is strongly dependent on the internal heterogeneity (mixing state) and morphology of individual particles containing black carbon (BC) and other non-absorbing species. Here, we examine an extensive ...
  • Stein, Itai Y; Wardle, Brian L (Elsevier, 2013-12)
    Intrinsic and scale-dependent properties of carbon nanotubes (CNTs) have led aligned CNT architectures to emerge as promising candidates for next-generation multifunctional applications. Enhanced operating regimes motivate ...
  • Duong, Hai M.; Yamamoto, Namiko; Bui, Khoa; Papavassiliou, Dimitrios V.; Maruyama, Shigeo; Wardle, Brian L. (American Chemical Society (ACS), 2010-04)
    Carbon nanotube (CNT)−CNT contact and CNT distribution effects on anisotropic thermal transport in aligned CNT−polymer nanocomposites (PNCs) are studied using an off-lattice Monte Carlo numerical simulation. Inter-CNT ...
  • Raviv, T. Riklin; Ljosa, V.; Conery, Annie L.; Ausubel, Frederick M.; Carpenter, Anne E.; Golland, Polina; Wahlby, C. (Springer-Verlag Berlin Heidelberg, 2010)
    We present a novel approach for extracting cluttered objects based on their morphological properties. Specifically, we address the problem of untangling Caenorhabditis elegans clusters in high-throughput screening experiments. ...
  • Burr, Devon M.; Drummond, Sarah A.; Cartwright, Richard; Black, Benjamin Alexander; Perron, J. Taylor (Elsevier B.V., 2013-09)
    Although Titan’s surface shows clear evidence of erosional modification, such as fluvial incision, evidence for tectonism has been less apparent. On Earth, fluvial networks with strongly preferred orientations are often ...
  • Ge, Tian; Holmes, Avram J.; Smoller, Jordan W.; Buckner, Randy L.; Alzheimer's Disease Neuroimaging Initiative; Sabuncu, Mert R; Fischl, Bruce (National Academy of Sciences (U.S.), 2016-09)
    Complex physiological and behavioral traits, including neurological and psychiatric disorders, often associate with distributed anatomical variation. This paper introduces a global metric, called morphometricity, as a ...
  • Ananthakrishnan, Ashwin N.; Cagan, Andrew; Gainer, Vivian S.; Cheng, Su-Chun; Cai, Tianxi; Szolovits, Peter; Shaw, Stanley Y.; Churchill, Susanne; Karlson, Elizabeth W.; Murphy, Shawn N.; Kohane, Isaac; Liao, Katherine P. (Elsevier, 2014-09)
    Introduction Primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) frequently co-occur. PSC is associated with increased risk for colorectal cancer (CRC). However, whether PSC is associated with increased ...
  • Raffone, Federico; Cicero, Giancarlo; Ataca, Can; Grossman, Jeffrey C. (American Chemical Society (ACS), 2016-05)
    Two-dimensional MoS₂ is a promising material for nanoelectronics and catalysis, but its potential is not fully exploited since proper control of its multiple phases (H, T, ZT) and electronic properties is lacking. In this ...
  • Winstein, Keith J.; Balakrishnan, Hari (Advanced Computing Systems Association, 2012-06)
    Mosh (mobile shell) is a remote terminal application that supports intermittent connectivity, allows roaming, and speculatively and safely echoes user keystrokes for better interactive response over high-latency paths. ...
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