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Browsing MIT Open Access Articles by Title

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  • Yokoyama, Kenichi; Uhlin, Ulla; Stubbe, JoAnne (American Chemical Society (ACS), 2010-06)
    E. coli ribonucleotide reductase catalyzes the reduction of nucleoside 5′-diphosphates into 2′-deoxynucleotides and is composed of two subunits: α2 and β2. During turnover, a stable tyrosyl radical (Y•) at Y[subscript ...
  • Theile, Christopher S.; Witte, Martin D.; Blom, Annet E. M.; Kundrat, Lenka; Guimaraes, Carla P.; Ploegh, Hidde (Nature Publishing Group, 2013-08)
    This protocol describes the use of sortase-mediated reactions to label the N terminus of any given protein of interest. The sortase recognition sequence, LPXTG (for Staphylococcus aureus sortase A) or LPXTA (for Streptococcus ...
  • Witte, Martin D; Wu, Tongfei; Guimaraes, Carla P; Theile, Christopher S; Blom, Annet E M; Ingram, Jessica R; Li, Zeyang; Kundrat, Lenka; Goldberg, Shalom D; Ploegh, Hidde (Springer Nature, 2015-02)
    Transpeptidation catalyzed by ​sortase A allows the preparation of proteins that are site-specifically and homogeneously modified with a wide variety of functional groups, such as fluorophores, PEG moieties, lipids, glycans, ...
  • Witte, Martin D; Wu, Tongfei; Guimaraes, Carla P; Theile, Christopher S; Blom, Annet E M; Ingram, Jessica R; Li, Zeyang; Kundrat, Lenka; Goldberg, Shalom D; Ploegh, Hidde (Nature Publishing Group, 2015-02)
    Transpeptidation catalyzed by ​sortase A allows the preparation of proteins that are site-specifically and homogeneously modified with a wide variety of functional groups, such as fluorophores, PEG moieties, lipids, glycans, ...
  • Coppi, Bruno; Zucchetti, M.; Bonavigo, Lucia; Franza, F.; Ciampichetti, A.; Bombarda, F.; Caldarella, M.; Chiaravalli, F.; Mancini, F.; Faelli, G. (Institute of Electrical and Electronics Engineers, 2009-08)
    Ignitor is a proposed compact high-magnetic field tokamak aimed at studying plasma burning conditions in Deuterium-Tritium plasmas. Localisation of this experiment in Italy has seen growing attention during the last years. ...
  • Anous, Tarek; Freedman, Daniel Z.; Maloney, Alexander (Springer-Verlag, 2014-07)
    We present the basic N = 1 superconformal field theories in four-dimensional de Sitter space-time, namely the non-abelian super Yang-Mills theory and the chiral multiplet theory with gauge interactions or cubic superpotential. ...
  • Margulies, Daniel S.; Goulas, Alexandros; Falkiewicz, Marcel; Huntenburg, Julia M.; Bezgin, Gleb; Eickhoff, Simon B.; Castellanos, F. Xavier; Petrides, Michael; Jefferies, Elizabeth; Smallwood, Jonathan; Ghosh, Satrajit S; Langs, Georg (National Academy of Sciences (U.S.), 2016-10)
    Understanding how the structure of cognition arises from the topographical organization of the cortex is a primary goal in neuroscience. Previous work has described local functional gradients extending from perceptual and ...
  • Walter, Matthew R.; Antone, Matthew; Chuangsuwanich, Ekapol; Correa, Andrew; Davis, Randall; Fletcher, Luke; Frazzoli, Emilio; Friedman, Yuli; How, Jonathan P.; Jeon, Jeong hwan; Karaman, Sertac; Luders, Brandon; Roy, Nicholas; Tellex, Stefanie; Teller, Seth; Glass, James R. (Wiley Blackwell, 2014-09)
    One long-standing challenge in robotics is the realization of mobile autonomous robots able to operate safely in human workplaces, and be accepted by the human occupants. We describe the development of a multiton robotic ...
  • Pongpaichet, Siripen; Singh, Vivek Kumar; Jain, Ramesh; Pentland, Alex Paul (Association for Computing Machinery, 2013-10)
    Geo-fencing has recently been applied to multiple applications including media recommendation, advertisements, wildlife monitoring, and recreational activities. However current geo-fencing systems work with static geographical ...
  • Musch, B. U.; Hagler, Ph.; Engelhardt, M.; Negele, John W.; Schafer, A. (American Physical Society, 2012-05)
    We present a first calculation of transverse momentum-dependent nucleon observables in dynamical lattice QCD employing nonlocal operators with staple-shaped, “process-dependent” Wilson lines. The use of staple-shaped Wilson ...
  • Hirose, Takashi; Galvin, Brendan D.; Horvitz, H. Robert (National Academy of Sciences (U.S.), 2010-08)
    The decision of a cell to undergo programmed cell death is tightly regulated during animal development and tissue homeostasis. Here, we show that the Caenorhabditis elegans Six family homeodomain protein C. elegans homeobox ...
  • Cordero, Zachary Copoulos; Knight, Braden E.; Schuh, Christopher A (Maney Publishing, 2016-07)
    Refining a metal’s grain size can result in dramatic increases in strength, and the magnitude of this strengthening increment can be estimated using the Hall–Petch equation. Since the Hall–Petch equation was proposed, there ...
  • Adams, Elisabeth Rose; Lopez-Morales, Mercedes; Elliot, James L.; Seager, Sara; Osip, David J. (IOP Publishing, 2010-09)
    We present six new transits of the hot Jupiter OGLE-TR-113b observed with MagIC on the Magellan Telescopes between 2007 January and 2009 May. We update the system parameters and revise the planetary radius to R[subscript ...
  • Neugebauer, Timothy C.; Perreault, David J.; Lang, Jeffrey H.; Livermore, Carol (Institute of Electrical and Electronics Engineers (IEEE), 2004-02)
    The construction of miniaturized rotating electric machines through microfabrication techniques is becoming a reality. Applications of such micromotors include miniaturized pumps, compressors, fans, coolers, and turbogenerators. ...
  • Banerjee, Abhijit; Karlan, Dean S.; Zinman, Jonathan (American Economic Association, 2015-01)
    Causal evidence on microcredit impacts informs theory, practice, and debates about its effectiveness as a development tool. The six randomized evaluations in this volume use a variety of sampling, data collection, experimental ...
  • Elishakoff, Isaac; Crandall, Stephen H (Springer Netherlands, 2016-03)
    Stochastic linearization technique is a versatile method of solving nonlinear stochastic boundary value problems. It allows obtaining estimates of the response of the system when exact solution is unavailable; in contrast ...
  • Alexander, Harriet; Sosik, Heidi; Fischer, Alexis Dal; Moberg, Emily A.; Brownlee, Emily F.; Hunter-Cevera, Kristen Rachel; Pitz, Kathleen Johnson; Rosengard, Sarah Zhou (The Oceanography Society, 2014-03)
    One of the most dramatic large-scale features in the ocean is the seasonal greening of the North Atlantic in spring and summer due to the accumulation of phytoplankton biomass in the surface layer. In 1953, Harald Ulrik ...
  • Kenyon, Richard; Miller, Jason; Wilson, David B.; Sheffield, Scott Roger (American Physical Society, 2017-05)
    Square ice is a statistical mechanics model for two-dimensional ice, widely believed to have a conformally invariant scaling limit. We associate a Peano (space-filling) curve to a square ice configuration, and more generally ...
  • Veiseh, Omid; Doloff, Joshua C.; Ma, Minglin; Tam, Hok Hei; Li, Jie; Langan, Erin; Wyckoff, Jeffrey; Loo, Whitney S.; Jhunjhunwala, Siddharth; Chiu, Alan; Siebert, Sean; Tang, Katherine; Hollister-Lock, Jennifer; Bochenek, Matthew; Mendoza-Elias, Joshua; Wang, Yong; Qi, Merigeng; Lavin, Danya M.; Chen, Michael; Dholakia, Nimit; Thakrar, Raj; Weir, Gordon C.; Oberholzer, Jose; Greiner, Dale L.; Langer, Robert; Vegas, Arturo; Bader, Andrew; Aresta-Dasilva, Stephanie K.; Anderson, Daniel Griffith; Lacik, Igor; Thankrar, Raj (Nature Publishing Group, 2015-05)
    The efficacy of implanted biomedical devices is often compromised by host recognition and subsequent foreign body responses. Here, we demonstrate the role of the geometry of implanted materials on their biocompatibility ...
  • Sickafoose, Amanda A (IOP Publishing, 2017-09)
    We use data from five stellar occultations observed between 2013 and 2016 to constrain Chariklo's size and shape, and the ring reflectivity. We consider four possible models for Chariklo (sphere, Maclaurin spheroid, triaxial ...
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