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Browsing MIT Open Access Articles by Title

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  • Piore, Michael J. (Wiley-Blackwell Pubishers, 2011-12)
    This article addresses the difficulties that industrial relations is experiencing both as a set of practices and as an intellectual tradition. It traces those difficulties to the changes in the basic structures of industrial ...
  • Angrist, Joshua; Pathak, Parag; Walters, Christopher Ross; Dynarski, Susan M.; Kane, Thomas J. (Wiley Blackwell, 2012-06)
    The nation's largest charter management organization is the Knowledge is Power Program (KIPP). KIPP schools are emblematic of the No Excuses approach to public education, a highly standardized and widely replicated charter ...
  • Seaton, Daniel; Bergner, Yoav; Chuang, Isaac; Mitros, Piotr; Pritchard, David E (Association for Computing Machinery (ACM), 2014-04)
    Massive open online courses (MOOCs) collect valuable data onstudent learning behavior: essentially complete records of all student interactions in a self-contained learning environment,with the benefit of large sample ...
  • Silva-Risso, Jorge; Zettelmeyer, Florian; Busse, Meghan R.; Knittel, Christopher Roland (Springer US, 2016-05)
    Many consumers are keenly aware of gasoline prices, and consumer responses to gasoline prices have been well studied. In this paper, by contrast, we investigate how gasoline prices affect the automobile industry: manufacturers ...
  • Hayter, Christopher S; Maroulis, Spiro; Lubynsky, Roman M (Springer-Verlag, 2016-03)
    Academic entrepreneurship, the establishment of new companies based on technologies derived from university research, is a well-recognized driver of regional and national economic development. For more than a decade, ...
  • Dai, Hongkai; Valenzuela, Andres; Tedrake, Russell Louis (Institute of Electrical and Electronics Engineers (IEEE), 2014-11)
    To plan dynamic, whole-body motions for robots, one conventionally faces the choice between a complex, full-body dynamic model containing every link and actuator of the robot, or a highly simplified model of the robot as ...
  • Albanese, Alexandre; Chung, Kwanghun (eLife Sciences Publications, Ltd., 2016-01)
    Advances in microscopy and sample preparation have led to the first ever mapping of individual neurons in the whole mouse brain.
  • Venkataraman, Archana; Whitford, Thomas J.; Westin, Carl-Fredrik; Golland, Polina; Kubicki, Marek (Elsevier, 2012-08)
    Background Schizophrenia has been associated with disturbances in brain connectivity; however the exact nature of these disturbances is not fully understood. Measuring temporal correlations between the functional MRI time ...
  • Lander, Eric S. (Nature Publishing Group, 2014-05)
    Translating whole-exome sequencing (WES) for prospective clinical use may have an impact on the care of patients with cancer; however, multiple innovations are necessary for clinical implementation. These include rapid and ...
  • Schubert, Christian R.; Chahrour, Maria H.; Yu, Timothy W.; Lim, Elaine T.; Ataman, Bulent; Coulter, Michael E.; Hill, R. Sean; Stevens, Christine R.; Greenberg, Michael E.; Gabriel, Stacey B.; Walsh, Christopher A. (Public Library of Science, 2012-04)
    Although autism has a clear genetic component, the high genetic heterogeneity of the disorder has been a challenge for the identification of causative genes. We used homozygosity analysis to identify probands from ...
  • Giannikou, Krinio; Malinowska, Izabela A.; Pugh, Trevor J.; Yan, Rachel; Tseng, Yuen-Yi; Kim, Jaegil; Tyburczy, Magdalena E.; Chekaluk, Yvonne; Liu, Yang; Alesi, Nicola; Finlay, Geraldine A.; Wu, Chin-Lee; Signoretti, Sabina; Henske, Elizabeth P.; Kwiatkowski, David J.; Oh, Coyin; Meyerson, Matthew L; Getz, Gad Asher; Boehm, Jesse S (Public Library of Science, 2016-08)
    Renal angiomyolipoma is a kidney tumor in the perivascular epithelioid (PEComa) family that is common in patients with Tuberous Sclerosis Complex (TSC) and Lymphangioleiomyomatosis (LAM) but occurs rarely sporadically. ...
  • Adalsteinsson, Viktor A.; Tallapragada, Naren; Tahirova, Narmin; Love, J. Christopher; Regev, Aviv (Nature Publishing Group, 2014-04)
    Comprehensive analyses of cancer genomes promise to inform prognoses and precise cancer treatments. A major barrier, however, is inaccessibility of metastatic tissue. A potential solution is to characterize circulating ...
  • Rodrigue, Sebastien; Malmstrom, Rex R.; Berlin, Aaron M.; Birren, Bruce W.; Henn, Matthew R.; Chisholm, Sallie (Penny) (Public Library of Science, 2009-09)
    Background Single-cell genome sequencing has the potential to allow the in-depth exploration of the vast genetic diversity found in uncultured microbes. We used the marine cyanobacterium Prochlorococcus as a model system ...
  • Kim, Hoon; Zheng, Siyuan; Amini, Seyed S.; Virk, Selene M.; Mikkelsen, Tom; Brat, Daniel J.; Grimsby, Jonna; Sougnez, Carrie; Muller, Florian; Hu, Jian; Sloan, Andrew E.; Cohen, Mark L.; Van Meir, Erwin G.; Scarpace, Lisa; Laird, Peter W.; Weinstein, John N.; Lander, Eric S.; Gabriel, Stacey B.; Getz, Gad; Meyerson, Matthew L.; Chin, Lynda; Barnholtz-Sloan, Jill S.; Verhaak, Roel G.W. (Cold Spring Harbor Laboratory Press, 2015-03)
    Glioblastoma (GBM) is a prototypical heterogeneous brain tumor refractory to conventional therapy. A small residual population of cells escapes surgery and chemoradiation, resulting in a typically fatal tumor recurrence ...
  • Dzink-Fox, J.; Bodi Winn, Caroline M; Feng, Yan; Shen, Zeli; Bakthavatchalu, Vasudevan; Fox, James G (American Society for Microbiology, 2017-01)
    In collaboration with the CDC’s Streptococcus Laboratory, we report here the whole-genome sequences of seven Streptococcus agalactiae bacteria isolated from laboratory-reared Long-Evans rats. Four of the S. agalactiae ...
  • Van der Auwera, G. A.; Kolter, R.; Mahillon, J.; Feldgarden, Michael (American Society for Microbiology, 2013-10)
    Bacillus cereus sensu lato is a species complex that includes the anthrax pathogen Bacillus anthracis and other bacterial species of medical, industrial, and ecological importance. Their phenotypes of interest are typically ...
  • Makarewicz, Oliwia; Lucas, Marie; Brandt, Christian; Herrmann, Leonie; Albersmeier, Andreas; Blom, Jochen; Goesmann, Alexander; van der Linden, Mark; Pletz, Mathias W.; Kalinowski, Jorn; Rueckert, Christian (Public Library of Science, 2017-01)
    Streptococcus pneumoniae is a major pathogen that causes different invasive pneumococcal diseases (IPD). The pneumococcal polysaccharide capsule is a main virulence factor. More than 94 capsule types have been described, ...
  • Kasar, S.; Kim, J.; Improgo, R.; Tiao, G.; Polak, P.; Haradhvala, N.; Lawrence, M. S.; Kiezun, A.; Fernandes, S. M.; Bahl, S.; Sougnez, C.; Gabriel, S.; Kim, H. T.; Getz, G.; Brown, J. R.; Lander, Eric Steven (Nature Publishing Group, 2015-12)
    Patients with chromosome 13q deletion or normal cytogenetics represent the majority of chronic lymphocytic leukaemia (CLL) cases, yet have relatively few driver mutations. To better understand their genomic landscape, here ...
  • Takahashi, Shoichi; Hulsey, Sarah (MIT Press, 2009-07)
    In this article, we develop a substantially expanded theory of late merger. Adopting related insights by Fox (2002), we argue that late merger is permitted whenever an output representation can be interpreted in the semantic ...
  • Medhora, M.; Gao, F.; Glisch, C.; Narayanan, J.; Sharma, A.; Harmann, L. M.; Lawlor, M. W.; Snyder, L. A.; Fish, B. L.; Moulder, J. E.; Strande, J. L.; Jacobs, E. R.; Down, Julian D. (Japan Radiation Research Society, 2014-11)
    To study the mechanisms of death following a single lethal dose of thoracic radiation, WAG/RijCmcr (Wistar) rats were treated with 15 Gy to the whole thorax and followed until they were morbid or sacrificed for invasive ...
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