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Browsing MIT Open Access Articles by Title

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  • Benner, Peter; Gugercin, Serkan; Willcox, Karen E. (Society for Industrial and Applied Mathematics, 2015-11)
    Numerical simulation of large-scale dynamical systems plays a fundamental role in studying a wide range of complex physical phenomena; however, the inherent large-scale nature of the models often leads to unmanageable ...
  • Bisias, Dimitrios; Flood, Mark; Lo, Andrew W.; Valavanis, Stavros (Annual Reviews, 2012-10)
    We provide a survey of 31 quantitative measures of systemic risk in the economics and finance literature, chosen to span key themes and issues in systemic risk measurement and management. We motivate these measures from ...
  • Vedenko, A.; Kurland, J. V.; Rogers, J. M.; Gisselbrecht, S. S.; Woodard, J.; Mariani, L.; Kock, K. H.; Inukai, S.; Siggers, T.; Shokri, L.; Gordan, R.; Sahni, N.; Cotsapas, C.; Hao, T.; Yi, S.; Vidal, M.; Hill, D. E.; Barrera, Luis Alberto; Rossin, Elizabeth; Kellis, Manolis; Daly, Mark J; Bulyk, Martha L (American Association for the Advancement of Science (AAAS), 2016-03)
    Sequencing of exomes and genomes has revealed abundant genetic variation affecting the coding sequences of human transcription factors (TFs), but the consequences of such variation remain largely unexplored. We developed ...
  • Hussain, Hameed; Rentifis, Ilias; Tziritas, Nikos; Loukopoulos, Thanasis; Xu, Cheng-Zhong; Qureshi, Muhammad Bilal; Qureshi, Muhammad Shuaib; Khan, Samee U.; Zomaya, Albert Y.; Allah, Nasro Min; Mehri Dehnavi, Maryam (Springer Netherlands, 2014-04)
    Grid is a distributed high performance computing paradigm that offers various types of resources (like computing, storage, communication) to resource-intensive user tasks. These tasks are scheduled to allocate available ...
  • Banerjee, Ashis; Chowdhury, Sagar; Losert, Wolfgang; Gupta, Satyandra K. (Society of Photo-optical Instrumentation Engineers, 2011-05)
    Optical tweezers have emerged as a promising technique for manipulating biological objects. Instead of direct laser exposure, more often than not, optically-trapped beads are attached to the ends or boundaries of the objects ...
  • Mikusheva, Anna (CEMI RAS, 2013)
    This paper provides a brief review of the current state of knowledge on the topic of weakly-identified instrumental variable regression. We describe the essence of the problem of weak identification, possible methods for ...
  • Materna, Arne; Varadharajan, Charuleka; Blackburn, Matthew; Rodríguez, Jorge; Preheim, Sarah P.; Olesen, Scott Wilder; Spencer, Sarah J.; Hemond, Harold F; Alm, Eric J; Friedman, Jonathan (Nature Publishing Group, 2016-08)
    Much remains unknown about what drives microbial community structure and diversity. Highly structured environments might offer clues. For example, it may be possible to identify metabolically similar species as groups of ...
  • Locknar, Angela M.; Mitchell, Rudolph; Rankin, Janet; Sadoway, Donald Robert (American Chemical Society, 2012-03)
    A first-year Chemistry course is ideal for introducing students to finding and using scholarly information research early in their academic careers. A four pronged approach was used to incorporate library research skills ...
  • Liang, Qingkai; Modiano, Eytan H (Institute of Electrical and Electronics Engineers (IEEE), 2016-07)
    Time-varying graphs are a useful model for networks with dynamic connectivity such as vehicular networks, yet, despite their great modeling power, many important features of time-varying graphs are still poorly understood. ...
  • Hyang-Won Lee, Marzieh; Parandehgheibi, Marzieh; Modiano, Eytan H (Institute of Electrical and Electronics Engineers (IEEE), 2014-12)
    One of the most important advances in modern communication networks is embedding multilayer network architectures such as IP-over-WDM.1 In these layered networks, a logical topology is embedded onto a physical topology ...
  • Parandehgheibi, Marzieh; Lee, Hyang-Won; Modiano, Eytan H. (Institute of Electrical and Electronics Engineers, 2012-03)
    We consider the problem of protection in multilayer networks. In single-layer networks, a pair of disjoint paths can be used to provide protection for a source-destination pair. However, this approach cannot be directly ...
  • Noll, Elisa M.; Sprick, Martin R.; Trumpp, Andreas; Muzumdar, Mandar; Chen, Pan-Yu; Dorans, Kimberly; Chung, Katherine Minjee; Bhutkar, Arjun; Hong, Erin; Jacks, Tyler E. (Nature Publishing Group, 2017-10)
    Activating mutations in the proto-oncogene KRAS are a hallmark of pancreatic ductal adenocarcinoma (PDAC), an aggressive malignancy with few effective therapeutic options. Despite efforts to develop KRAS-targeted drugs, ...
  • Coe, Allison; Ghizzoni, Julie; LeGault, Kristen Nicole; Biller, Steven; Roggensack, Sara; Chisholm, Sallie W (Association for the Sciences of Limnology and Oceanography, 2016-07)
    Prochlorococcus is the smallest oxygenic phototroph in the ocean, where it can be found in great abundance throughout the euphotic zone in mid-latitude waters. Populations of this picocyanobacterium have been observed below ...
  • Rinard, Martin C. (Institute of Electrical and Electronics Engineers, 2009-08)
    Survival is a key concern of many complex systems. A standard approach to maximizing the likelihood of survival is to attempt to produce a system that is as free of errors as possible. We instead propose a methodology that ...
  • Bevis, Brooke J. (Rockefeller University Press, The, 2017-06-19)
    The science universe is dimmer after one of our brightest stars, Susan Lee Lindquist, was taken by cancer on October 27, 2016. Sue was an innovative, creative, out-of-the-box scientific thinker. She had unique biological ...
  • Olcum, Selim; Cermak, Nathan; Wasserman, Steven Charles; Payer, Kristofor Robert; Shen, Wenjiang; Lee, Jungchul; Manalis, Scott R. (Institute of Electrical and Electronics Engineers (IEEE), 2014-01)
    Nanomechanical resonators can quantify individual particles down to a single atom; however the applications are limited due to their degraded performance in solution. Suspended micro- and nanochannel resonators can achieve ...
  • Seidel, Paul (Springer-Verlag, 2009-10)
    We describe the behaviour of Fukaya categories under “suspension”, which means passing from the fibre of a Lefschetz fibration to the double cover of the total space branched along that fibre. As an application, we consider ...
  • Passerini, Stefano; Kazimi, Mujid S. (MDPI AG, 2012-09)
    The nuclear fuel cycle is the series of stages that nuclear fuel materials go through in a cradle to grave framework. The Once Through Cycle (OTC) is the current fuel cycle implemented in the United States; in which an ...
  • Srinivasan, Siddarth; Gilbert, Jonathan Brian; Cohen, Robert E.; McKinley, Gareth H.; Kleingartner, Justin Alan; Milne, Andrew James Barnabas (American Physical Society, 2015-01)
    We demonstrate a reduction in the measured inner wall shear stress in moderately turbulent Taylor-Couette flows by depositing sprayable superhydrophobic microstructures on the inner rotor surface. The magnitude of reduction ...
  • Hu, Joyce K.; Crampton, Jordan; Sanders, Rogier W.; Moore, John P.; Crotty, Shane; Tam, Hok Hei; Melo, Mariane Bandeira; Kang, Myung Sun; Pelet, Jeisa; Ruda, Vera; Foley, Maria Hottelet; Kumari, Sudha; Baldeon, Alexis D; Langer, Robert S; Anderson, Daniel Griffith; Chakraborty, Arup K; Irvine, Darrell J (National Academy of Sciences (U.S.), 2016-10)
    Natural infections expose the immune system to escalating antigen and inflammation over days to weeks, whereas nonlive vaccines are single bolus events. We explored whether the immune system responds optimally to antigen ...
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