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Browsing MIT Open Access Articles by Title

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  • Dittrich, M. A.; Gutowski, Timothy G.; Cao, J.; Roth, J. T.; Xia, Z. C.; Kiridena, V.; Ren, F.; Henning, H. (Springer Science + Business Media B.V., 2012-03)
    Research in the last 15 years has led to die-less incremental forming processes that are close to realization in an industrial setup. Whereas many studies have been carried out with the intention of investigating technical ...
  • Chatterjee, Nilanjan; Jagoutz, Oliver E (Springer Berlin Heidelberg, 2015-01)
    Ultrahigh-pressure (UHP) rocks such as the coesite-bearing eclogites, occurring as boudins within felsic gneisses of the Tso Morari dome in northwestern Himalayas, originated through subduction of the northern continental ...
  • Eliashberg, Yakov; Borman, Matthew Strom; Murphy, Emmy Le (Springer Netherlands, 2016-02)
    We establish a parametric extension h-principle for overtwisted contact structures on manifolds of all dimensions, which is the direct generalization of the 3-dimensional result from. It implies, in particular, that any ...
  • del Pino, Álvaro; Presas, Francisco; Pérez, José Luis; Casals Gutierrez, Roger (Springer Berlin Heidelberg, 2017-05)
    In this article we prove that the inclusion of the space of Engel structures of a smooth 4-manifold into the space of full flags of its tangent bundle induces surjections in all homotopy groups. In particular, we construct ...
  • Pérez, José L; del Pino, Álvaro; Presas, Francisco; Pérez, José Luis; Casals Gutierrez, Roger (Springer-Verlag, 2017-05)
    In this article we prove that the inclusion of the space of Engel structures of a smooth 4-manifold into the space of full flags of its tangent bundle induces surjections in all homotopy groups. In particular, we construct ...
  • Birkar, Caucher; Cascini, Paolo; Hacon, Christopher D.; McKernan, James (American Mathematical Society, 2010-01)
    We prove that the canonical ring of a smooth projective variety is finitely generated.
  • Hacon, Christopher D.; McKernan, James (American Mathematical Society, 2010-01)
    Assuming finite generation in dimension $ n-1$, we prove that pl-flips exist in dimension $ n$.
  • Li, Haozhao; Zhou, Xin (Springer Berlin Heidelberg, 2016-05)
    We show that in a closed 3-manifold with a generic metric of positive Ricci curvature, there are minimal surfaces of arbitrary large Morse index, which partially confirms a conjecture by Marques and Neves. We prove this ...
  • Stapelfeldt, Karl R.; Brenner, Michael P.; Warfield, Keith R.; Dekens, Frank G.; Belikov, Ruslan; Brugarolas, Paul B.; Bryden, Geoffrey; Chakrabarti, Supriya; Dubovitsky, Serge; Effinger, Robert T.; Hirsch, Brian; Kissil, Andrew; Krist, John E.; Lang, Jared J.; Marley, Mark S.; McElwain, Michael W.; Meadows, Victoria S.; Nissen, Joel; Oseas, Jeffrey M.; Serabyn, Eugene; Sunada, Eric; Trauger, John T.; Unwin, Stephen C.; Cahoy, Kerri (SPIE, 2014-06)
    "Exo-C" is NASA's first community study of a modest aperture space telescope designed for high contrast observations of exoplanetary systems. The mission will be capable of taking optical spectra of nearby exoplanets in ...
  • Stapelfeldt, Karl R.; Dekens, Frank G.; Brenner, Michael P.; Warfield, Keith R.; Belikov, Ruslan; Brugarolas, Paul B.; Bryden, Geoffrey; Chakrabarti, Supriya; Dubovitsky, Serge; Effinger, Robert T.; Hirsch, Brian; Kissil, Andrew; Krist, John E.; Lang, Jared J.; Marley, Mark S.; McElwain, Michael W.; Meadows, Victoria S.; Nissen, Joel; Oseas, Jeffrey M.; Pong, Chris; Serabyn, Eugene; Sunada, Eric; Trauger, John T.; Unwin, Stephen C.; Cahoy, Kerri (SPIE, 2015-08)
    "Exo-C" is NASAs first community study of a modest aperture space telescope mission that is optimized for high contrast observations of exoplanetary systems. The mission will be capable of taking optical spectra of nearby ...
  • Li, Deyu; Delaney, James C.; Page, Charlotte M.; Yang, Xuedong; Chen, Alvin S.; Wong, Cintyu; Drennan, Catherine L.; Essigmann, John M. (American Chemical Society (ACS), 2012-04)
    The DNA and RNA repair protein AlkB removes alkyl groups from nucleic acids by a unique iron- and α-ketoglutarate-dependent oxidation strategy. When alkylated adenines are used as AlkB targets, earlier work suggests that ...
  • Sontag, Emily M.; Joachimiak, Lukasz A.; Tan, Zhiqun; Tomlinson, Anthony; Housman, David E.; Glabe, Charles G.; Potkin, Steven G.; Frydman, Judith; Thompson, Leslie M. (National Academy of Sciences (U.S.), 2013-01)
    Aggregation of misfolded proteins is characteristic of a number of neurodegenerative diseases, including Huntington disease (HD). The CCT/TRiC (chaperonin containing TCP-1/TCP-1 ring) chaperonin complex can inhibit aggregation ...
  • Stein, Itai Y.; Lachman-Senesh, Noa; Devoe, Mackenzie E.; Wardle, Brian L. (American Chemical Society (ACS), 2014-05)
    Here we present a study on the presence of physisorbed water on the surface of aligned carbon nanotubes (CNTs) in ambient conditions, where the wet CNT array mass can be more than 200% larger than that of dry CNTs, and ...
  • Lander, Eric S. (Nature Publishing Group, 2013-03)
    The incidence of esophageal adenocarcinoma (EAC) has risen 600% over the last 30 years. With a 5-year survival rate of ~15%, the identification of new therapeutic targets for EAC is greatly important. We analyze the mutation ...
  • Altshuler, David (Springer-Verlag, 2012-11)
    Aims/hypothesis: Human complex metabolic traits are in part regulated by genetic determinants. Here we applied exome sequencing to identify novel associations of coding polymorphisms at minor allele frequencies (MAFs) >1% ...
  • Lander, Eric Steven (Nature Publishing Group, 2015-08)
    Myocardial infarction (MI), a leading cause of death around the world, displays a complex pattern of inheritance. When MI occurs early in life, the role of inheritance is substantially greater. Previously, rare mutations ...
  • Lander, Eric S.; Barbieri, Christopher E.; Baca, Sylvan C.; Lawrence, Michael S.; Demichelis, Francesca; Blattner, Mirjam; Theurillat, Jean-Philippe; White, Thomas A.; Stojanov, Petar; Van Allen, Eliezer; Stransky, Nicolas; Nickerson, Elizabeth; Chae, Sung-Suk; Boysen, Gunther; Auclair, Daniel; Onofrio, Robert; Park, Kyung; Kitabayashi, Naoki; MacDonald, Theresa Y.; Sheikh, Karen (Nature Publishing Group, 2012-05)
    Prostate cancer is the second most common cancer in men worldwide and causes over 250,000 deaths each year. Overtreatment of indolent disease also results in significant morbidity. Common genetic alterations in prostate ...
  • Fabrycky, Daniel C.; Winn, Joshua Nathan (American Astronomical Society, 2009-04)
    One possible diagnostic of planet formation, orbital migration, and tidal evolution is the angle ψ between a planet's orbital axis and the spin axis of its parent star. In general, ψ cannot be measured, but for transiting ...
  • Seager, Sara; Deming, Drake (Annual Reviews, 2010-06)
    At the dawn of the first discovery of exoplanets orbiting Sun-like stars in the mid-1990s, few believed that observations of exoplanet atmospheres would ever be possible. After the 2002 Hubble Space Telescope detection of ...
  • Smith, Matthew William; Seager, Sara; Pong, Christopher Masaru; Villasenor, Jesus Noel Samonte; Ricker, George R.; Miller, David W.; Knapp, Mary E.; Farmer, Grant Trapnell; Jensen-Clem, Rebecca M. (SPIE, 2010-07)
    Nanosatellites, i.e. spacecraft that weigh between 1 and 10 kg, are drawing increasing interest as platforms for conducting on-orbit science. This trend is primarily driven by the ability to piggyback nanosatellites on the ...
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