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Browsing MIT Open Access Articles by Title

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  • Chappaz, Loic; Sood, Rohan; Howell, Kathleen C.; Milbury, Colleen; Melosh IV, Henry Jay; Blair, David M.; Zuber, Maria (American Geophysical Union (AGU), 2017-01)
    NASA's GRAIL mission employed twin spacecraft in polar orbits around the Moon to measure the lunar gravity field at unprecedentedly high accuracy and resolution. The low spacecraft altitude in the extended mission enables ...
  • Oduro, Harry D.; Cody, George D.; Farquhar, James; Harms, Brian; Kaufman, Alan J.; Sintim, Herman O. (National Academy of Sciences, 2011-10)
    Thermochemical sulfate reduction experiments with simple amino acid and dilute concentrations of sulfate reveal significant degrees of mass-independent sulfur isotope fractionation. Enrichments of up to 13‰ for [superscript ...
  • Ernst, Jason; Liu, Yaping; Sarkar, Abhishek Kulshreshtha; Kheradpour, Pouya; Kellis, Manolis (BioMed Central, 2017-10)
    Background Recombination rate is non-uniformly distributed across the human genome. The variation of recombination rate at both fine and large scales cannot be fully explained by DNA sequences alone. ...
  • Lepore, Emiliano; Marchioro, Andrea; Isaia, Marco; Pugno, Nicola M.; Buehler, Markus J. (Public Library of Science, 2012-02)
    Spider silks display generally strong mechanical properties, even if differences between species and within the same species can be observed. While many different types of silks have been tested, the mechanical properties ...
  • Taylor, Frank E. (American Physical Society, 2015-07)
    This Letter reports evidence of triple gauge boson production pp → W(ℓν)γγ + X, which is accessible for the first time with the 8 TeV LHC data set. The fiducial cross section for this process is measured in a data sample ...
  • Beatty, Anne; Liao, Scott; Weber, Joseph P. (Elsevier, 2011-12)
    We investigate delegated monitoring by examining the determinants and effects of including cross-acceleration provisions in public debt contracts. We find that cross-acceleration provision use depends on borrowers' going ...
  • Hohnloser, Stefan H.; Ikeda, Takanori; Cohen, Richard J. (Elsevier, 2008-10)
    Background: Microvolt T-wave alternans (MTWA) testing in many studies has proven to be a highly accurate predictor of ventricular tachyarrhythmic events (VTEs) in patients with risk factors for sudden cardiac death (SCD) ...
  • Morten, Christopher J.; Byers, Jeffery A.; Jamison, Timothy F. (American Chemical Society (ACS), 2011-01)
    A detailed kinetic study of the endo-selective epoxide-opening cascade reaction of a diepoxy alcohol in neutral water was undertaken using 1H NMR spectroscopy. The observation of monoepoxide intermediates resulting from ...
  • Golob, Jonathan L.; Pabon, Lil M.; Pratt, Gabriel A.; Loring, Jeanne F.; Laurent, Louise C.; Murry, Charles E.; Kumar, Roshan; Guenther, Matthew; Young, Richard A (Public Library of Science (PLoS), 2011-08)
    A surprising portion of both mammalian and Drosophila genomes are transcriptionally paused, undergoing initiation without elongation. We tested the hypothesis that transcriptional pausing is an obligate transition state ...
  • Gonçalves, Geisa A. L.; Oliveira, Pedro H.; Gomes, Ana G.; Lewis, Leslie A.; Monteiro, Gabriel A.; Jones, Kristala L.; Prazeres, Duarte Miguel (Springer Berlin Heidelberg, 2014-04)
    Insertion specificity of mobile genetic elements is a rather complex aspect of DNA transposition, which, despite much progress towards its elucidation, still remains incompletely understood. We report here the results of ...
  • Dewey, Dan; Dwarkadas, V. V.; Haberl, F.; Sturm, R.; Canizares, Claude R. (IOP Publishing, 2012-05)
    Observations of SN 1987A by the Chandra High Energy Transmission Grating (HETG) in 1999 and the XMM-Newton Reflection Grating Spectrometer (RGS) in 2003 show very broad (v-b) lines with a full width at half-maximum (FWHM) ...
  • Landau, Dan A.; Carter, Scott L.; Stojanov, Petar; McKenna, Aaron; Stevenson, Kristen; Lawrence, Michael S.; Sougnez, Carrie; Stewart, Chip; Sivachenko, Andrey; Wang, Lili; Wan, Youzhong; Zhang, Wandi; Shukla, Sachet A.; Vartanov, Alexander; Fernandes, Stacey M.; Saksena, Gordon; Cibulskis, Kristian; Tesar, Bethany; Gabriel, Stacey B.; Hacohen, Nir; Meyerson, Matthew L.; Lander, Eric S.; Neuberg, Donna S.; Brown, Jennifer R.; Getz, Gad; Wu, Catherine J. (Elsevier, 2013-02)
    Clonal evolution is a key feature of cancer progression and relapse. We studied intratumoral heterogeneity in 149 chronic lymphocytic leukemia (CLL) cases by integrating whole-exome sequence and copy number to measure the ...
  • Jumlongras, Dolrudee; Lachke, Salil A.; O’Connell, Daniel J.; Aboukhalil, Anton; Li, Xiao; Choe, Sung E.; Ho, Joshua W. K.; Turbe-Doan, Annick; Robertson, Erin A.; Olsen, Bjorn R.; Bulyk, Martha L.; Amendt, Brad A.; Maas, Richard L. (Public Library of Science, 2012-06)
    To elucidate the transcriptional regulation of Bmp4 expression during organogenesis, we used phylogenetic footprinting and transgenic reporter analyses to identify Bmp4 cis-regulatory modules (CRMs). These analyses identified ...
  • Jarosz, Daniel F.; Lancaster, Alex K.; Brown, Jessica Conrad; Lindquist, Susan (Elsevier, 2014-08)
    [GAR[superscript +]] is a protein-based element of inheritance that allows yeast (Saccharomyces cerevisiae) to circumvent a normal hallmark of their biology: extreme metabolic specialization for glucose fermentation. When ...
  • Means, Terry K.; Mylonakis, Eleftherios; Tampakakis, Emmanouil; Colvin, Richard A.; Seung, Edward; Puckett, Lindsay; Tai, Melissa F.; Stewart, Cameron R.; Pukkila-Worley, Read; Hickman, Suzanne E.; Moore, Kathryn J.; Calderwood, Stephen B.; Hacohen, Nir; Luster, Andrew D.; El Khoury, Joseph (Rockefeller University Press, 2009-03)
    Receptors involved in innate immunity to fungal pathogens have not been fully elucidated. We show that the Caenorhabditis elegans receptors CED-1 and C03F11.3, and their mammalian orthologues, the scavenger receptors SCARF1 ...
  • Shishkin, Alexander A.; Zhu, Xiaopeng; Kadri, Sabah; Maza, Itay; Guttman, Mitchell; Hanna, Jacob H.; Garber, Manuel; Chen, Jenny; Regev, Aviv (Biomed Central Ltd., 2016-02)
    Background: Recent advances in transcriptome sequencing have enabled the discovery of thousands of long non-coding RNAs (lncRNAs) across many species. Though several lncRNAs have been shown to play important roles in diverse ...
  • O'Reilly, Una-May; Medard, Muriel; Traskov, Danail; Kim, Minkyu (2009-06)
    Whereas the theory and application of optimal network coding are well studied for the single-session multicast scenario, there is no known optimal network coding strategy for a more general connection problem where there ...
  • Butler, Thomas Charles; Benayoun, Marc; Wallace, Edward; van Drongelen, Wim; Goldenfeld, Nigel; Cowan, Jack (National Academy of Sciences of the United States of America, 2011-12)
    In the cat or primate primary visual cortex (V1), normal vision corresponds to a state where neural excitation patterns are driven by external visual stimuli. A spectacular failure mode of V1 occurs when such patterns are ...
  • Tsankov, Alexander M.; Yanagisawa, Yoshimi; Rhind, Nicholas; Regev, Aviv; Rando, Oliver J. (Cold Spring Harbor Laboratory Press, 2011-09)
    The packaging of eukaryotic genomes into nuclesomes plays critical roles in chromatin organization and gene regulation. Studies in Saccharomyces cerevisiae indicate that nucleosome occupancy is partially encoded by intrinsic ...
  • Washietl, Stefan; Kellis, Manolis; Garber, Manuel (Cold Spring Harbor Laboratory Press, 2014-01)
    Long intergenic noncoding RNAs (lincRNAs) play diverse regulatory roles in human development and disease, but little is known about their evolutionary history and constraint. Here, we characterize human lincRNA expression ...
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