Browsing MIT Open Access Articles by Title
Now showing items 11810-11829 of 32362
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H-MOOC framework: reusing MOOCs for hybrid education
(Springer US, 2017-01)Since Massive Open Online Courses (MOOCs) started to become part of the scene of Higher Education (HE), many institutions have joined the race of MOOC creation. However, producing MOOCs has shown to be a cumbersome and ... -
H. hepaticus-induced liver tumor promotion is associated with increased serum bile acid and a persistent microbial-induced immune response
(American Association for Cancer Research, 2011-02)Chronic microbial infection influences cancer progression, but the mechanisms that link them remain unclear. Constitutive androstane receptor (CAR) is a nuclear receptor that regulates enzymes involved in endobiotic and ... -
H2A.Z Acidic Patch Couples Chromatin Dynamics to Regulation of Gene Expression Programs during ESC Differentiation
(Public Library of Science, 2013-08)The histone H2A variant H2A.Z is essential for embryonic development and for proper control of developmental gene expression programs in embryonic stem cells (ESCs). Divergent regions of amino acid sequence of H2A.Z likely ... -
H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions
(Biomed Central Ltd., 2012-10)Background: The histone variant H2A.Z has been implicated in nucleosome exchange, transcriptional activation and Polycomb repression. However, the relationships among these seemingly disparate functions remain obscure. Results: ... -
H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions
(BioMed Central Ltd, 2012-10)Abstract Background The histone variant H2A.Z has been implicated in nucleosome exchange, transcriptional activation and Polycomb repression. However, the relationships among these seemingly disparate functions remain ... -
H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs
(Elsevier, 2016-01)Histone variant H2A.Z occupies the promoters of active and poised, bivalent genes in embryonic stem cells (ESCs) to regulate developmental programs, yet how it contributes to these contrasting states is poorly understood. ... -
H2A.Z: a molecular rheostat for transcriptional control
(Faculty of 1000, Ltd., 2015-01)The replacement of nucleosomal H2A with the histone variant H2A.Z is critical for regulating DNA-mediated processes across eukaryotes and for early development of multicellular organisms. How this variant performs these ... -
H5N1 highly pathogenic avian influenza virus isolated from conjunctiva of a whooper swan with neurological signs
(Springer Vienna, 2012-10)An H5N1 highly pathogenic avian influenza virus was isolated from conjunctiva of a whooper swan with neurological signs, which was captured during the latest H5N1 HPAI outbreak in Japan. The conjunctival swab contained a ... -
H[subscript 2]-assisted CO[subscript 2] thermochemical reduction on La[subscript 0.9]Ca[subscript 0.1]FeO[subscript 3-δ] membranes: a kinetics study
(Wiley Blackwell, 2017-11)Kinetics data for CO2 thermochemical reduction in an isothermal membrane reactor is required to identify the rate-limiting steps. Here, we report a detailed reaction kinetics study on this process supported by an ... -
H[subscript 2]-optimal decentralized control over posets: A state space solution for state-feedback
(Institute of Electrical and Electronics Engineers (IEEE), 2010-12)We develop a complete state-space solution to ℋ[subscript 2]-optimal decentralized control of poset-causal systems with state-feedback. Our solution is based on the exploitation of a key separability property of the problem, ... -
H[subscript 2]-Optimal Decentralized Control Over Posets: A State-Space Solution for State-Feedback
(Institute of Electrical and Electronics Engineers (IEEE), 2013-09)We develop a complete state-space solution to H[subscript 2]-optimal decentralized control of poset-causal systems with state-feedback. Our solution is based on the exploitation of a key separability property of the problem ... -
Habenula “Cholinergic” Neurons Corelease Glutamate and Acetylcholine and Activate Postsynaptic Neurons via Distinct Transmission Modes
(Elsevier, 2011-02)Acetylcholine is an important neurotransmitter, and the habenulo-interpeduncular projection is a major cholinergic pathway in the brain. To study the physiological properties of cholinergic transmission in the interpeduncular ... -
Habit formation
(AICH - Servier Research Group, 2016-03)Habits, both good ones and bad ones, are pervasive in animal behavior. Important frameworks have been developed to understand habits through psychological and neurobiological studies. This work has given us a rich understanding ... -
Habit formation coincides with shifts in reinforcement representations in the sensorimotor striatum
(American Physiological Society, 2016-03)Evaluating outcomes of behavior is a central function of the striatum. In circuits engaging the dorsomedial striatum, sensitivity to goal value is accentuated during learning, whereas outcome sensitivity is thought to be ... -
Habit Learning by Naive Macaques Is Marked by Response Sharpening of Striatal Neurons Representing the Cost and Outcome of Acquired Action Sequences
(Elsevier/Cell Press, 2015-08)Over a century of scientific work has focused on defining the factors motivating behavioral learning. Observations in animals and humans trained on a wide range of tasks support reinforcement learning (RL) algorithms as ... -
Habit learning is associated with major shifts in frequencies of oscillatory activity and synchronized spike firing in striatum
(National Academy of Sciences (U.S.), 2011-10)Rhythmic brain activity is thought to reflect, and to help organize, spike activity in populations of neurons during on-going behavior. We report that during learning, a major transition occurs in task-related oscillatory ... -
A Habit-Based Explanation of the Exchange Rate Risk Premium
(American Finance Association/Wiley, 2010-01)This paper presents a model that reproduces the uncovered interest rate parity puzzle. Investors have preferences with external habits. Countercyclical risk premia and procyclical real interest rates arise endogenously. ... -
The Habitable Exoplanet (HabEx) Imaging Mission: preliminary science drivers and technical requirements
(SPIE, 2016-08)HabEx is one of four candidate flagship missions being studied in detail by NASA, to be submitted for consideration to the 2020 Decadal Survey in Astronomy and Astrophysics for possible launch in the 2030s. It will be ... -
Habituation based synaptic plasticity and organismic learning in a quantum perovskite
(Nature Publishing Group, 2017-08)A central characteristic of living beings is the ability to learn from and respond to their environment leading to habit formation and decision making. This behavior, known as habituation, is universal among all forms of ... -
Habituation without NMDA Receptor-Dependent Desensitization of Hering- Apnea Reflex in a Mecp2 [superscript + / -] Mutant Mouse Model of Rett Syndrome
(Frontiers Research Foundation, 2011-05)Non-associative learning is a basic neuroadaptive behavior exhibited in almost all animal species and sensory modalities but its functions and mechanisms in the mammalian brain are poorly understood. Previous studies have ...
