Now showing items 14782-14801 of 34782

    • INFINITESIMAL CHEREDNIK ALGEBRAS AS W-ALGEBRAS 

      Losev, I.; Tsymbaliuk, Oleksandr (Springer US, 2014-03)
      In this article we establish an isomorphism between universal infinitesimal Cherednik algebras and W-algebras for Lie algebras of the same type and 1-block nilpotent elements. As a consequence we obtain some fundamental ...
    • Inflamed neutrophils sequestered at entrapped tumor cells via chemotactic confinement promote tumor cell extravasation 

      Chen, Michelle B; Hajal, Cynthia; Benjamin, David Colin; Yu, Cathy Y.; Azizgolshani, Hesham; e.a. (Proceedings of the National Academy of Sciences, 2018-05)
      Systemic inflammation occurring around the course of tumor progression and treatment are often correlated with adverse oncological outcomes. As such, it is suspected that neutrophils, the first line of defense against ...
    • Inflammasome Sensor NLRP1 Controls Rat Macrophage Susceptibility to Toxoplasma gondii 

      Cirelli, Kimberly; Gorfu, Gezahegn; Hassan, Musa A.; Printz, Morton; Crown, Devorah; e.a. (Public Library of Science, 2014-03)
      Toxoplasma gondii is an intracellular parasite that infects a wide range of warm-blooded species. Rats vary in their susceptibility to this parasite. The Toxo1 locus conferring Toxoplasma resistance in rats was previously ...
    • Inflammation Triggers Zeb1-Dependent Escape from Tumor Latency 

      Shibue, Tsukasa; Dongre, Anushka; Keckesova, Zuzana; Reinhardt, Ferenc; De Cock, Jasmine Morgan; e.a. (American Association for Cancer Research (AACR), 2016-08)
      The emergence of metastatic disease in cancer patients many years or decades after initial successful treatment of primary tumors is well documented but poorly understood at the molecular level. Recent studies have begun ...
    • Inflammation-Induced Cell Proliferation Potentiates DNA Damage-Induced Mutations In Vivo 

      Kiraly, Orsolya; Gong, Guanyu; Olipitz, Werner; Muthupalani, Sureshkumar; Engelward, Bevin P. (Public Library of Science, 2015-02)
      Mutations are a critical driver of cancer initiation. While extensive studies have focused on exposure-induced mutations, few studies have explored the importance of tissue physiology as a modulator of mutation susceptibility ...
    • An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel disease 

      Ermann, J.; Zhou, A.; Hamilton, M. J.; Cao, B.; Korzenik, J. R.; e.a. (American Association for the Advancement of Science (AAAS), 2015-07)
      There is a clinical need for new, more effective treatments for chronic and debilitating inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis. Targeting drugs selectively to the inflamed ...
    • Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition 

      Jenney, Anne P.; Sorger, Peter K.; Jones II, Douglas S.; Joughin, Brian Alan; Lauffenburger, Douglas A (American Association for the Advancement of Science, 2018-03)
      Rheumatoid arthritis (RA) is a chronic inflammatory disorder that causes joint pain, swelling, and loss of function. Development of effective new drugs has proven challenging in part because of the complexities and ...
    • Inflammatory regulatory network mediated by the joint action of NF-kB, STAT3, and AP-1 factors is involved in many human cancers 

      Regev, Aviv (Proceedings of the National Academy of Sciences, 2019-05)
      Using an inducible, inflammatory model of breast cellular transformation, we describe the transcriptional regulatory network mediated by STAT3, NF-κB, and AP-1 factors on a genomic scale. These proinflammatory regulators ...
    • The Inflammatory Response to Double Stranded DNA in Endothelial Cells Is Mediated by NFκB and TNFα 

      Patel, Suraj J.; Jindal, Rohit; King, Kevin R.; Tilles, Arno W.; Yarmush, Martin L. (Public Library of Science, 2011-05)
      Endothelial cells represent an important barrier between the intravascular compartment and extravascular tissues, and therefore serve as key sensors, communicators, and amplifiers of danger signals in innate immunity and ...
    • Inflation driven by unification energy 

      Hertzberg, Mark Peter; Wilczek, Frank (American Physical Society, 2017-03)
      We examine the hypothesis that inflation is primarily driven by vacuum energy at a scale indicated by gauge coupling unification. Concretely, we consider a class of hybrid inflation models wherein the vacuum energy associated ...
    • Inflation Expectations, Learning, and Supermarket Prices: Evidence from Survey Experiments 

      Cavallo, Alberto F.; Cruces, Guillermo; Perez-Truglia, Ricardo (American Economic Association, 2017-07)
      Information frictions play a central role in the formation of household inflation expectations, but there is no consensus about their origins. We address this question with novel evidence from survey experiments. We document ...
    • Inflation, symmetry, and B-modes 

      Hertzberg, Mark Peter (Elsevier, 2015-04)
      We examine the role of using symmetry and effective field theory in inflationary model building. We describe the standard formulation of starting with an approximate shift symmetry for a scalar field, and then introducing ...
    • Inflationary paradigm after Planck 2013 

      Nomura, Yasunori; Guth, Alan; Kaiser, David I. (Elsevier, 2014-04)
      Models of cosmic inflation posit an early phase of accelerated expansion of the universe, driven by the dynamics of one or more scalar fields in curved spacetime. Though detailed assumptions about fields and couplings vary ...
    • INFLOW-OUTFLOW MODEL WITH CONDUCTION AND SELF-CONSISTENT FEEDING FOR Sgr A* 

      Shcherbakov, Roman V.; Baganoff, Frederick K. (IOP Publishing, 2010-05)
      We propose a two-temperature radial inflow-outflow model near Sgr A* with self-consistent feeding and conduction. Stellar winds from individual stars are considered to find the rates of mass injection and energy injection. ...
    • Influence in a large society: Interplay between information dynamics and network structure 

      Dolecek, Lara; Shah, Devavrat (Institute of Electrical and Electronics Engineers, 2009-08)
      Motivated by the recent emergence of large online social networks, we seek to understand the effects the underlying social network (graph) structure and the information dynamics have on the creation of influence of an ...
    • Influence of 9p21.3 Genetic Variants on Clinical and Angiographic Outcomes in Early-Onset Myocardial Infarction 

      Ardissino, Diego; Berzuini, Carlo; Merlini, Piera Angelica; Mannuccio Mannucci, Pier; Surti, Aarti; e.a. (Elsevier, 2011-07)
      Objectives: The purpose of this study was to test whether the 9p21.3 variant rs1333040 influences the occurrence of new cardiovascular events and coronary atherosclerosis progression after early-onset myocardial ...
    • Influence of air quality model resolution on uncertainty associated with health impacts 

      Thompson, Tammy M.; Selin, Noelle Eckley (Copernicus GmbH, 2012-10)
      We use regional air quality modeling to evaluate the impact of model resolution on uncertainty associated with the human health benefits resulting from proposed air quality regulations. Using a regional photochemical model ...
    • The influence of astrocytes on the width of orientation hypercolumns in visual cortex: A computational perspective 

      Philips, Ryan T.; Sur, Mriganka; Chakravarthy, V. Srinivasa (Public Library of Science, 2017-10)
      Orientation preference maps (OPMs) are present in carnivores (such as cats and ferrets) and primates but are absent in rodents. In this study we investigate the possible link between astrocyte arbors and presence of OPMs. ...
    • Influence of bottom topography on vortex stability 

      Zhao, Bowen; Chieusse-Gerard, Emma; Flierl, Glenn (American Meteorological Society, 2019-12)
      The effects of topography on the linear stability of both barotropic vortices and two-layer, baroclinic vortices are examined by considering cylindrical topography and vortices with stepwise relative vorticity profiles in ...
    • The Influence of Catalysts on Discharge and Charge Voltages of Rechargeable Li–Oxygen Batteries 

      Gasteiger, Hubert A.; Parent, Michael C.; Chiloyan, Vazrik; Shao-Horn, Yang; Lu, Yi-chun (Electrochemical Society, 2010-04)
      This study revealed the strong influence of carbon, Au/C, and Pt/C catalysts on the charge and discharge voltages of rechargeable Li–O[subscript 2] batteries. Li–O[subscript 2] single-cell measurements showed that Au/C had ...