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Hybridized Discontinuous Galerkin Methods for Wave Propagation
(Springer Science+Business Media, 2018-09-05)
We present the recent development of hybridizable and embedded discontinuous Galerkin (DG) methods for wave propagation problems in fluids, solids, and electromagnetism. In each of these areas, we describe the methods, ...
Interpreting Deep Visual Representations via Network Dissection
(Institute of Electrical and Electronics Engineers, 2019-09-01)
The success of recent deep convolutional neural networks (CNNs) depends on learning hidden representations that can summarize the important factors of variation behind the data. In this work, we describe Network Dissection, ...
High‐fat diet in a mouse insulin‐resistant model induces widespread rewiring of the phosphotyrosine signaling network
(EMBO, 2019-08)
Obesity-associated type 2 diabetes and accompanying diseases have developed into a leading human health risk across industrialized and developing countries. The complex molecular underpinnings of how lipid overload and ...
On metric properties of maps between Hamming spaces and related graph homomorphisms
(Elsevier BV, 2017-01)
A mapping of k-bit strings into n-bit strings is called an (α,β)-map if k-bit strings which are more than αk apart are mapped to n-bit strings that are more than βn apart in Hamming distance. This is a relaxation of the ...
Combinatorial prediction of marker panels from single‐cell transcriptomic data
(EMBO, 2019-10)
Single-cell transcriptomic studies are identifying novel cell populations with exciting functional roles in various in vivo contexts, but identification of succinct gene marker panels for such populations remains a challenge. ...
Multi-cell ECM compaction is predictable via superposition of nonlinear cell dynamics linearized in augmented state space
(Public Library of Science (PLoS), 2019-09-20)
Cells interacting through an extracellular matrix (ECM) exhibit emergent behaviors resulting from collective intercellular interaction. In wound healing and tissue development, characteristic compaction of ECM gel is induced ...
Multi-modality in gene regulatory networks with slow promoter kinetics
(Public Library of Science (PLoS), 2019-02-19)
Phenotypical variability in the absence of genetic variation often reflects complex energetic landscapes associated with underlying gene regulatory networks (GRNs). In this view, different phenotypes are associated with ...
Dynamic filopodial forces induce accumulation, damage, and plastic remodeling of 3D extracellular matrices
(Public Library of Science (PLoS), 2019-04-08)
The mechanical properties of the extracellular matrix (ECM)–a complex, 3D, fibrillar scaffold of cells in physiological environments–modulate cell behavior and can drive tissue morphogenesis, regeneration, and disease ...
A Bayesian model of acquisition and clearance of bacterial colonization incorporating within-host variation
(Public Library of Science (PLoS), 2019-04-22)
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
Energetics of optimal undulatory swimming organisms
(Public Library of Science (PLoS), 2019-10-31)
Energy consumption is one of the primary considerations in animal locomotion. In swimming locomotion, a number of questions related to swimming energetics of an organism and how the energetic quantities scale with body ...