Now showing items 1-3 of 3
Combinatorial prediction of marker panels from single‐cell transcriptomic data
Single-cell transcriptomic studies are identifying novel cell populations with exciting functional roles in various in vivo contexts, but identification of succinct gene marker panels for such populations remains a challenge. ...
Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation
(Springer Science and Business Media LLC, 2019-11-29)
Human iPSC-derived kidney organoids have the potential to revolutionize discovery, but assessing their consistency and reproducibility across iPSC lines, and reducing the generation of off-target cells remain an open ...
Nuclei multiplexing with barcoded antibodies for single-nucleus genomics
(Springer Science and Business Media LLC, 2019-07-02)
Single-nucleus RNA-seq (snRNA-seq) enables the interrogation of cellular states in complex tissues that are challenging to dissociate or are frozen, and opens the way to human genetics studies, clinical trials, and precise ...