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Designing yeast as plant-like hyperaccumulators for heavy metals
(Springer Science and Business Media LLC, 2019-11-08)
Hyperaccumulators typically refer to plants that absorb and tolerate elevated amounts of heavy metals. Due to their unique metal trafficking abilities, hyperaccumulators are promising candidates for bioremediation applications. ...
ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry
(Springer Science and Business Media LLC, 2019-12)
A heritable polymorphism within regulatory sequences of the LMO1 gene is associated with its elevated expression and increased susceptibility to develop neuroblastoma, but the oncogenic pathways downstream of the LMO1 ...
Repeated evolution of cytochrome P450-mediated spiroketal steroid biosynthesis in plants
(Springer Science and Business Media LLC, 2019-07-19)
Diosgenin is a spiroketal steroidal natural product extracted from plants and used as the single most important precursor for the world steroid hormone industry. The sporadic occurrences of diosgenin in distantly related ...
Complex DNA knots detected with a nanopore sensor
(Springer Science and Business Media LLC, 2019-10-02)
Equilibrium knots are common in biological polymers—their prevalence, size distribution, structure, and dynamics have been extensively studied, with implications to fundamental biological processes and DNA sequencing ...
Mortality causes universal changes in microbial community composition
(Springer Science and Business Media LLC, 2019-05-09)
All organisms are sensitive to the abiotic environment, and a deteriorating environment can cause extinction. However, survival in a multispecies community depends upon interactions, and some species may even be favored ...
Discovery of TaFeSb-based half-Heuslers with high thermoelectric performance
(Springer Science and Business Media LLC, 2019-01-17)
Discovery of thermoelectric materials has long been realized by the Edisonian trial and error approach. However, recent progress in theoretical calculations, including the ability to predict structures of unknown phases ...
Creating fluorescent quantum defects in carbon nanotubes using hypochlorite and light
(Springer Science and Business Media LLC, 2019-06-28)
Covalent doping of single-walled carbon nanotubes (SWCNTs) can modify their optical properties, enabling applications as single-photon emitters and bio-imaging agents. We report here a simple, quick, and controllable method ...
Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation
(Springer Science and Business Media LLC, 2019-11-29)
Human iPSC-derived kidney organoids have the potential to revolutionize discovery, but assessing their consistency and reproducibility across iPSC lines, and reducing the generation of off-target cells remain an open ...
Towards integrated tunable all-silicon free-electron light sources
(Springer Science and Business Media LLC, 2019-07-18)
Extracting light from silicon is a longstanding challenge in modern engineering and physics. While silicon has underpinned the past 70 years of electronics advancement, a facile tunable and efficient silicon-based light ...
Percolation thresholds for photonic quantum computing
(Springer Science and Business Media LLC, 2019-03-06)
Despite linear-optical fusion (Bell measurement) being probabilistic, photonic cluster states for universal quantum computation can be prepared without feed-forward by fusing small n-photon entangled clusters, if the success ...