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Nuclei multiplexing with barcoded antibodies for single-nucleus genomics
(Springer Science and Business Media LLC, 2019-07-02)
Single-nucleus RNA-seq (snRNA-seq) enables the interrogation of cellular states in complex tissues that are challenging to dissociate or are frozen, and opens the way to human genetics studies, clinical trials, and precise ...
Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation
(Springer Science and Business Media LLC, 2019-11-29)
Human iPSC-derived kidney organoids have the potential to revolutionize discovery, but assessing their consistency and reproducibility across iPSC lines, and reducing the generation of off-target cells remain an open ...