MIT Libraries homeMIT Libraries logoDSpace@MIT

MIT
Search 
  • DSpace@MIT Home
  • MIT Open Access Articles
  • MIT Open Access Articles
  • Search
  • DSpace@MIT Home
  • MIT Open Access Articles
  • MIT Open Access Articles
  • Search
JavaScript is disabled for your browser. Some features of this site may not work without it.

Search

Show Advanced FiltersHide Advanced Filters

Filters

Use filters to refine the search results.

Now showing items 1-7 of 7

  • Sort Options:
  • Relevance
  • Title Asc
  • Title Desc
  • Issue Date Asc
  • Issue Date Desc
  • Results Per Page:
  • 5
  • 10
  • 20
  • 40
  • 60
  • 80
  • 100
Thumbnail

Gene-guided discovery and engineering of branched cyclic peptides in plants 

Kersten, Roland D.; Weng, Jing-Ke (Proceedings of the National Academy of Sciences, 2018-10-29)
The plant kingdom contains vastly untapped natural product chemistry, which has been traditionally explored through the activity-guided approach. Here, we describe a gene-guided approach to discover and engineer a class ...
Thumbnail

NUFIP1 is a ribosome receptor for starvation-induced ribophagy 

Wyant, Gregory A.; Abu-Remaileh, Monther; Frenkel, Evgeni M.; Laqtom, Nouf N.; Dharamdasani, Vimisha; e.a. (American Association for the Advancement of Science (AAAS), 2018-04-26)
The lysosome degrades and recycles macromolecules, signals to the master growth regulator mTORC1 [mechanistic target of rapamycin (mTOR) complex 1], and is associated with human disease.We performed quantitative proteomic ...
Thumbnail

CDK12 regulates DNA repair genes by suppressing intronic polyadenylation 

Dubbury, Sara J.; Boutz, Paul L.; Sharp, Phillip A. (Springer Science and Business Media LLC, 2018-11-28)
Mutations that attenuate homologous recombination (HR)-mediated repair promote tumorigenesis and sensitize cells to chemotherapeutics that cause replication fork collapse, a phenotype known as ‘BRCAness’1. BRCAness tumours ...
Thumbnail

Predictions of novel Schistosoma mansoni-human protein interactions consistent with experimental data 

White Bear, Javona; Long, Thavy; Skinner, Danielle; McKerrow, James H. (Springer Science and Business Media LLC, 2018-08-30)
Infection by the human blood fluke, Schistosoma mansoni involves a variety of cross-species protein- protein interactions. The pathogen expresses a diverse arsenal of proteins that facilitate the breach of physical and ...
Thumbnail

Altered exocrine function can drive adipose wasting in early pancreatic cancer 

Danai, Laura V.; Dennstedt, Emily A.; Muir, Alexander; Lien, Evan C.; Mayers, Jared R.; e.a. (Springer Science and Business Media LLC, 2018-06)
Changes in cell and organismal metabolism accompany malignancy1,2. Pancreatic ductal adenocarcinoma (PDAC) is associated with peripheral tissue wasting, a metabolic syndrome that lowers quality of life and is proposed to ...
Thumbnail

Histidine catabolism is a major determinant of methotrexate sensitivity 

Kanarek, Naama; Keys, Heather R.; Cantor, Jason R.; Lewis, Caroline A.; Chan, Sze Ham; e.a. (Springer Science and Business Media LLC, 2018-07)
The chemotherapeutic drug methotrexate inhibits the enzyme dihydrofolate reductase1, which generates tetrahydrofolate, an essential cofactor in nucleotide synthesis2. Depletion of tetrahydrofolate causes cell death by ...
Thumbnail

Secondary magnetite in ancient zircon precludes analysis of a Hadean geodynamo 

Borlina, Cauê S.; Weiss, Benjamin P.; Lima, Eduardo A. (Proceedings of the National Academy of Sciences, 2018-12-31)
Zircon crystals from the Jack Hills, Western Australia, are one of the few surviving mineralogical records of Earth’s first 500 million years and have been proposed to contain a paleomagnetic record of the Hadean geodynamo. ...

Browse

All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

My Account

Login

Discover

AuthorAbu-Remaileh, Monther (2)Chan, Sze Ham (2)Lewis, Caroline A. (2)Sabatini, David M. (2)Borlina, Cauê S. (1)Boutz, Paul L. (1)Cantor, Jason R. (1)Danai, Laura V. (1)Dennstedt, Emily A. (1)Dharamdasani, Vimisha (1)... View MoreSubject
Multidisciplinary (7)
... View MoreDate Issued
2018 (7)
Has File(s)Yes (7)

Statistics

OA StatisticsStatistics by CountryStatistics by Department
MIT Libraries homeMIT Libraries logo

Find us on

Twitter Facebook Instagram YouTube RSS

MIT Libraries navigation

SearchHours & locationsBorrow & requestResearch supportAbout us
PrivacyPermissionsAccessibility
MIT
Massachusetts Institute of Technology
Content created by the MIT Libraries, CC BY-NC unless otherwise noted. Notify us about copyright concerns.