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TGF-β signaling in cellular senescence and aging-related pathology
(MDPI AG, 2019-10-10)
Aging is broadly defined as the functional decline that occurs in all body systems. The accumulation of senescent cells is considered a hallmark of aging and thought to contribute to the aging pathologies. Transforming ...
Alzheimer’s Amyloid Hypothesis and Antibody Therapy: Melting Glaciers?
(MDPI AG, 2024-03-31)
The amyloid cascade hypothesis for Alzheimer’s disease is still alive, although heavily challenged. Effective anti-amyloid immunotherapy would confirm the hypothesis’ claim that the protein amyloid-beta is the ...
Shedding Light on Chemoresistance: The Perspective of Photodynamic Therapy in Cancer Management
(MDPI AG, 2024-03-29)
The persistent failure of standard chemotherapy underscores the urgent need for innovative and targeted approaches in cancer treatment. Photodynamic therapy (PDT) has emerged as a promising photochemistry-based approach ...