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Achieving high-temperature ferromagnetic topological insulating phase by proximity coupling
(Springer Science and Business Media LLC, 2016-05-09)
Using massive online choice experiments to measure changes in well-being
(Proceedings of the National Academy of Sciences, 2019-03-26)
Gross domestic product (GDP) and derived metrics such as productivity have been central to our understanding of economic progress and well-being. In principle, changes in consumer surplus provide a superior, and more direct, ...
OrgaQuant: Human Intestinal Organoid Localization and Quantification Using Deep Convolutional Neural Networks
(Springer Science and Business Media LLC, 2019-08-28)
Organoid cultures are proving to be powerful in vitro models that closely mimic the cellular constituents of their native tissue. Organoids are typically expanded and cultured in a 3D environment using either naturally ...
Quantitative screening of the effects of hyper-osmotic stress on cancer cells cultured in 2- or 3-dimensional settings
(Springer Science and Business Media LLC, 2019-09-24)
The maintenance of precise cell volume is critical for cell survival. Changes in extracellular osmolarity affect cell volume and may impact various cellular processes such as mitosis, mitochondrial functions, DNA repair ...
Top-down fabrication of high-uniformity nanodiamonds by self-assembled block copolymer masks
(Springer Science and Business Media LLC, 2019-05-06)
Nanodiamonds hosting colour centres are a promising material platform for various quantum technologies. The fabrication of non-aggregated and uniformly-sized nanodiamonds with systematic integration of single quantum ...
Measuring light transport properties using speckle patterns as structured illumination
(Springer Science and Business Media LLC, 2019-08-01)
The measurement of light absorption and scattering properties of biological materials has several diagnostic and therapeutic applications. We can measure these properties for skin without contact using structured illumination ...
Biosynthesis of the nitrogenase active-site cofactor precursor NifB-co in Saccharomyces cerevisiae
(Proceedings of the National Academy of Sciences, 2019-11-25)
The radical S-adenosylmethionine (SAM) enzyme NifB occupies a central and essential position in nitrogenase biogenesis. NifB catalyzes the formation of an [8Fe-9S-C] cluster, called NifB-co, which constitutes the core of ...
Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens
(Proceedings of the National Academy of Sciences, 2019-09-03)
Queuosine (Q) is a complex tRNA modification widespread in eukaryotes and bacteria that contributes to the efficiency and accuracy of protein synthesis. Eukaryotes are not capable of Q synthesis and rely on salvage of the ...
Expanding the stoichiometric window for metal cross-linked gel assembly using competition
(Proceedings of the National Academy of Sciences, 2019-10-07)
Polymer networks with dynamic cross-links have generated widespread interest as tunable and responsive viscoelastic materials. However, narrow stoichiometric limits in cross-link compositions are typically imposed in the ...
GDGT cyclization proteins identify the dominant archaeal sources of tetraether lipids in the ocean
(Proceedings of the National Academy of Sciences, 2019-10-07)
Glycerol dibiphytanyl glycerol tetraethers (GDGTs) are distinctive archaeal membrane-spanning lipids with up to eight cyclopentane rings and/or one cyclohexane ring. The number of rings added to the GDGT core structure can ...