Design of Specific Mammalian Promoters by in silico Prediction

Heinemann, Tim; Kramer, Stephen; Velten, Lars; Kranz, Anna-Lena; Bauer, Tobias; Faura, Marti Bernardo; Konig, Rainer; Keienburg, Jens; Eils, Roland; Iwamoto, Nao

Author(s)

Heinemann, Tim; Kramer, Stephen; Velten, Lars; Kranz, Anna-Lena; Bauer, Tobias; ... Show more

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Abstract

The purpose of this RFC is to provide a) a method for the design of rational synthetic promoter sequences based on a statistical analysis about the spatial preference of transcription factor binding sites in human promoter sequences and b) further introduce standards to provide compatibility with data formats introduced in this RFC. Description of promoters generated by this method can be found at http://2009.igem.org/Team:Heidelberg/HEARTBEAT_database.

Date issued

2009-10-30

URI

http://hdl.handle.net/1721.1/49520

Series/Report no.

BBF RFC;43

Keywords

modeling

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Requests for Comments (RFCs)

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Creative Commons