Design of Specific Mammalian Promoters by in silico Prediction
Name
BBFRFC43.pdf
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523.37 KB
Format
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Checksum (MD5)
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Author(s)
Heinemann, Tim
Kramer, Stephen
Velten, Lars
Kranz, Anna-Lena
Bauer, Tobias
Faura, Marti Bernardo
Konig, Rainer
Keienburg, Jens
Eils, Roland
Iwamoto, Nao
Date Issued
October 30, 2009
Series/Report no.
BBF RFC;43
Abstract
The purpose of this RFC is to provide a) a method for the design of rational
synthetic promoter sequences based on a statistical analysis about
the spatial preference of transcription factor binding sites in human promoter sequences and b) further introduce standards to provide compatibility
with data formats introduced in this RFC. Description of promoters generated by this method can be found at http://2009.igem.org/Team:Heidelberg/HEARTBEAT_database.
Subjects
modeling
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