Research background, approach, and methodologies for ensuring safety, integrity, and value optimization in the global biopharmaceutical supply chain

Abstract

As the biomanufacturing (BioMAN) initiative within the MIT Center for Biomedical Innovation enters its third year of active research, the competitive landscape and sources of resources to support biomanufacturing research have rapidly changed. This research is an attempt to provide insight into the following primary questions: **What research strategies could BioMAN effectively employ moving forward? **What is a specific example of BioMAN research targeted towards new potential resource sources? **What are the details of the research approach for a project that would be of interest to both existing and new resource sources? By leveraging a competitive analysis framework, a recommendation was developed for BioMAN to pursue the market segment of system-based research-centric programs without offering training or custom projects. Specific potential resource sources and collaboration partners were identified towards meeting this target market. An example interdisciplinary research program proposal was constructed with the intent to submit to the Alfred P. Sloan Foundation. Additionally, the details of planned approach to a project focused on biomanufacture location decisions were developed towards attracting support from both industrial partners and non-profit foundations.