An examination of peptide-tether binding to gold and glass surfaces
Author(s)Kunkel, Jacquelyn Anne
Massachusetts Institute of Technology. Dept. of Mechanical Engineering.
Matthew J. Lang.
MetadataShow full item record
For many biological applications, it is beneficial to know that a peptide will bind to a surface. In this thesis, a tether, bead, peptide complex is constructed using the gold binding peptide (GBP) of sequence (CGGVSGSSPDS). Several assays and assay modifications are developed and tested to attempt to attach the GBP first to a gold slide and then to gold nanoparticles. Four peptides: FO₂, K1, K2, K3, known to bind to sapphire were attached to glass to see if it was possible to modify the sapphire assay to work with glass.
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2009.Cataloged from PDF version of thesis.Includes bibliographical references (p. 14).
DepartmentMassachusetts Institute of Technology. Dept. of Mechanical Engineering.
Massachusetts Institute of Technology