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Ex vivo Imaging of Human Pathologies with Integrated Optical Coherence Tomography (OCT) and Optical Coherence Microscopy (OCM)

dc.contributor.authorBryan, Bradley
dc.contributor.authorWang, Yihong
dc.contributor.authorConnolly, James L.
dc.contributor.authorZhou, Chao
dc.contributor.authorAguirre, Aaron Dominic
dc.contributor.authorTsai, Tsung-Han
dc.contributor.authorFujimoto, James G.
dc.date.accessioned2010-05-13T19:52:04Z
dc.date.available2010-05-13T19:52:04Z
dc.date.issued2009-02
dc.date.submitted2009-01
dc.identifier.isbn9780819474148
dc.identifier.isbn0819474142
dc.identifier.issn0361-0748
dc.identifier.urihttp://hdl.handle.net/1721.1/54788
dc.description.abstractWe report an imaging study using integrated 3D-OCT and OCM for the assessment of various human thyroid and breast pathologies. The 3D-OCT data sets enable en face projection imaging, which provides large field of view with uniform focus and signal level, while OCM provides high magnification that enables cellular resolution imaging. We have demonstrated that the integrated 3D-OCT and OCM technology provide a substantial improvement over standard OCT for the visualization of tissue pathology and can serve as a useful imaging tool in the clinical settings.en
dc.description.sponsorshipMedical Free Electron Laser Program (contract FA9550-07- 1-0101 (JGF))en
dc.description.sponsorshipUnited States. Air Force Office of Scientific Research (contract FA9550-07-1-0014 (JGF))en
dc.description.sponsorshipUnited States. National Institutes of Health (grants R01-CA75289-12 (JGF and JLC))en
dc.language.isoen_US
dc.publisherSociety of Photo-optical Instrumentation Engineersen
dc.relation.isversionofhttp://dx.doi.org/10.1117/12.809064en
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en
dc.sourceSPIEen
dc.titleEx vivo Imaging of Human Pathologies with Integrated Optical Coherence Tomography (OCT) and Optical Coherence Microscopy (OCM)en
dc.typeArticleen
dc.identifier.citationZhou, Chao et al. “Ex vivo imaging of human pathologies with integrated optical coherence tomography (OCT) and optical coherence microscopy (OCM).” Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII. Ed. James G. Fujimoto, Joseph A. Izatt, & Valery V. Tuchin. San Jose, CA, USA: SPIE, 2009. 71680N-8. © 2009 Society of Photo-optical Instrumentation Engineers.en
dc.contributor.departmentHarvard University--MIT Division of Health Sciences and Technologyen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Electrical Engineering and Computer Scienceen_US
dc.contributor.departmentMassachusetts Institute of Technology. Research Laboratory of Electronicsen_US
dc.contributor.approverFujimoto, James G.
dc.contributor.mitauthorZhou, Chao
dc.contributor.mitauthorAguirre, Aaron Dominic
dc.contributor.mitauthorTsai, Tsung-Han
dc.contributor.mitauthorFujimoto, James G.
dc.relation.journalProceedings of the Society of Photo-optical Instrumentation Engineersen
dc.eprint.versionFinal published versionen
dc.type.urihttp://purl.org/eprint/type/JournalArticleen
eprint.statushttp://purl.org/eprint/status/PeerRevieweden
dspace.orderedauthorsZhou, Chao; Aguirre, Aaron D.; Wang, Yihong; Bryan, Bradley; Tsai, Tsung-Han; Connolly, James L.; Fujimoto, James G.en
dc.identifier.orcidhttps://orcid.org/0000-0002-0828-4357
mit.licensePUBLISHER_POLICYen
mit.metadata.statusComplete


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