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Computational and Systems Biology

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Computational and Systems Biology


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Recent Submissions

  • Smillie, Christopher Scott (Massachusetts Institute of Technology, 2016)
    The vast community of microbes that inhabit the human body, the human microbiota, is important to human health and disease. These microbes contribute to human metabolism, the development of the immune system and pathogen ...
  • Xie, Shicong, Ph. D. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2016)
    Spatiotemporally coordinated cell behavior is observed during morphogenesis, in both embryonic development as well as tissue regeneration. An open question is how individual cells collectively generate force to achieve the ...
  • Zhao, Boyang (Massachusetts Institute of Technology, 2016)
    Cancer is a clonal evolutionary process. This results in complex clonal architecture and intratumoral heterogeneity in each patient. This also presents challenges for effective therapeutic intervention - with constant ...
  • Agarwal, Vikram (Massachusetts Institute of Technology, 2015)
    MicroRNAs (miRNAs) are ~21-24 nt non-coding RNAs that mediate the degradation and translational repression of target mRNAs. The genomes of vertebrate organisms encode hundreds of miRNAs, each of which may regulate hundreds ...
  • Fan, Zi Peng (Massachusetts Institute of Technology, 2015)
    Mammals contain a wide array of cell types with distinct functions, yet nearly all cell types have the same genomic DNA. How the genetic instructions in DNA are selectively interpreted by cells to specify various cellular ...