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Computational and Systems Biology

Research and Teaching Output of the MIT Community

Computational and Systems Biology


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Recent Submissions

  • Agarwal, Vikram (Massachusetts Institute of Technology, 2015)
    MicroRNAs (miRNAs) are ~21-24 nt non-coding RNAs that mediate the degradation and translational repression of target mRNAs. The genomes of vertebrate organisms encode hundreds of miRNAs, each of which may regulate hundreds ...
  • Fan, Zi Peng (Massachusetts Institute of Technology, 2015)
    Mammals contain a wide array of cell types with distinct functions, yet nearly all cell types have the same genomic DNA. How the genetic instructions in DNA are selectively interpreted by cells to specify various cellular ...
  • Isik, Leyla (Massachusetts Institute of Technology, 2015)
    Humans can quickly and effortlessly recognize objects, and people and their actions from complex visual inputs. Despite the ease with which the human brain solves this problem, the underlying computational steps have ...
  • Gurry, Thomas (Massachusetts Institute of Technology, 2015)
    Protein aggregation underlies a number of human diseases. Most notably, it occurs widely in neurodegenerative diseases, including Alzheimer's and Parkinson's. At the molecular level, neurotoxicity is thought to originate ...
  • Negron, Christopher (Massachusetts Institute of Technology, 2014)
    Living cells integrate a vast array of protein-protein interactions (PPIs) to govern cellular functions. For instance, PPIs are critical to biosynthesis, nanostructural assembly, and in processing environmental stimuli ...