Effects of calcium carbonate particulate releasing surgical anchors on bone and tendon healing
Author(s)Medeiros, Jordan-Ryan J. I. K
Massachusetts Institute of Technology. Dept. of Materials Science and Engineering.
Linn W. Hobbs.
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The Calaxo ® screw, developed by Smith and Nephew, is a novel biomedical composite composed of poly-DL-lactide-co-glycolide (PLLA:PGA) 85:15 and calcium carbonate particulates. Comparisons to an identical surgical anchor composed of PLLA, largely considered an industry standard, shows increased mean failure strength in surgical reconstructions of the patellar-tibia complex in sheep. SEM imaging confirms the osteoconductivity of the Calaxo ® screw proposed in previous studies and also suggest a positive effect on the differentiation of tissues along the tendon-bone interface. These findings support the intended use of the Calaxo ® screw as a fixation device for rotator cuff repair procedures.
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2007.Cataloged from PDF version of thesis.Includes bibliographical references (p. 31-32).
DepartmentMassachusetts Institute of Technology. Dept. of Materials Science and Engineering.
Massachusetts Institute of Technology
Materials Science and Engineering.