Cell-Trappable Fluorescent Probes for Nitric Oxide Visualization in Living Cells
Author(s)Pluth, Michael D.; McQuade, Lindsey E.; Lippard, Stephen J.
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Two new cell-trappable fluorescent probes for nitric oxide (NO) are reported based on either incorporation of hydrolyzable esters or conjugation to aminodextran polymers. Both probes are highly selective for NO over other reactive oxygen and nitrogen species (RONS). The efficacy of these probes for the fluorescence imaging of nitric oxide produced endogenously in Raw 264.7 cells is demonstrated.
DepartmentMassachusetts Institute of Technology. Department of Chemistry
American Chemical Society
Pluth, Michael D., Lindsey E. McQuade, and Stephen J. Lippard. “Cell-Trappable Fluorescent Probes for Nitric Oxide Visualization in Living Cells.” Organic Letters 12.10 (2010) : 2318-2321.
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