Cell-Trappable Fluorescent Probes for Nitric Oxide Visualization in Living Cells

Author(s)
Pluth, Michael D.; McQuade, Lindsey E.; Lippard, Stephen J.
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Abstract
Two new cell-trappable fluorescent probes for nitric oxide (NO) are reported based on either incorporation of hydrolyzable esters or conjugation to aminodextran polymers. Both probes are highly selective for NO over other reactive oxygen and nitrogen species (RONS). The efficacy of these probes for the fluorescence imaging of nitric oxide produced endogenously in Raw 264.7 cells is demonstrated.
Date issued
2010-03
URI
http://hdl.handle.net/1721.1/64765
Department
Massachusetts Institute of Technology. Department of Chemistry
Journal
Organic Letters
Publisher
American Chemical Society
Citation
Pluth, Michael D., Lindsey E. McQuade, and Stephen J. Lippard. “Cell-Trappable Fluorescent Probes for Nitric Oxide Visualization in Living Cells.” Organic Letters 12.10 (2010) : 2318-2321.
Version: Author's final manuscript
ISSN
1523-7060
1523-7052
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