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dc.contributor.authorBorg-Graham, Lyle J.en_US
dc.date.accessioned2004-10-20T20:22:35Z
dc.date.available2004-10-20T20:22:35Z
dc.date.issued1989-09-01en_US
dc.identifier.otherAITR-1161en_US
dc.identifier.urihttp://hdl.handle.net/1721.1/7023
dc.description.abstractA modeling study of hippocampal pyramidal neurons is described. This study is based on simulations using HIPPO, a program which simulates the somatic electrical activity of these cells. HIPPO is based on a) descriptions of eleven non-linear conductances that have been either reported for this class of cell in the literature or postulated in the present study, and b) an approximation of the electrotonic structure of the cell that is derived in this thesis, based on data for the linear properties of these cells. HIPPO is used a) to integrate empirical data from a variety of sources on the electrical characteristics of this type of cell, b) to investigate the functional significance of the various elements that underly the electrical behavior, and c) to provide a tool for the electrophysiologist to supplement direct observation of these cells and provide a method of testing speculations regarding parameters that are not accessible.en_US
dc.format.extent36745155 bytes
dc.format.extent29879792 bytes
dc.format.mimetypeapplication/postscript
dc.format.mimetypeapplication/pdf
dc.language.isoen_US
dc.relation.ispartofseriesAITR-1161en_US
dc.titleModelling the Somantic Electrical Response of Hippocampal Pyramidal Neuronsen_US


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