Pd-Catalyzed Cross-Coupling Reactions of Amides and Aryl Mesylates

Author(s)
Dooleweerdt, Karin; Fors, Brett P.; Buchwald, Stephen Leffler
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Abstract
A catalyst, based on a biarylphosphine ligand, for the Pd-catalyzed cross-coupling reactions of amides and aryl mesylates is described. This system allows an array of aryl and heteroaryl mesylates to be transformed into the corresponding N-aryl amides in moderate to excellent yields.
Date issued
2010-04
URI
http://hdl.handle.net/1721.1/71908
Department
Massachusetts Institute of Technology. Department of Chemistry
Journal
Organic Letters
Publisher
American Chemical Society (ACS)
Citation
Dooleweerdt, Karin, Brett P. Fors, and Stephen L. Buchwald. “Pd-Catalyzed Cross-Coupling Reactions of Amides and Aryl Mesylates.” Organic Letters 12.10 (2010): 2350–2353.
Version: Author's final manuscript
ISSN
1523-7060
1523-7052
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