A Multi-Ligand Based Pd Catalyst for C–N Cross-Coupling Reactions
Author(s)Fors, Brett P.; Buchwald, Stephen Leffler
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An alternative approach to catalyst development, which led to a Pd catalyst based on two biarylphosphine ligands for C−N cross-coupling reactions, is reported. By effectively being able to take the form of multiple catalysts this system manifests the best properties that catalysts based on either of the two ligands exhibit separately and displays the highest reactivity and substrate scope of any system that has been reported to date for these reactions.
DepartmentMassachusetts Institute of Technology. Department of Chemistry
Journal of the American Chemical Society
American Chemical Society (ACS)
Fors, Brett P., and Stephen L. Buchwald. “A Multiligand Based Pd Catalyst for C−N Cross-Coupling Reactions.” Journal of the American Chemical Society 132.45 (2010): 15914–15917.
Author's final manuscript