Show simple item record

dc.contributor.authorHenderson, Jaclyn L.
dc.contributor.authorMcDermott, Sarah M.
dc.contributor.authorBuchwald, Stephen Leffler
dc.date.accessioned2012-08-14T16:04:11Z
dc.date.available2012-08-14T16:04:11Z
dc.date.issued2010-09
dc.date.submitted2010-08
dc.identifier.issn1523-7060
dc.identifier.issn1523-7052
dc.identifier.urihttp://hdl.handle.net/1721.1/72118
dc.description.abstractSimple and efficient procedures for the Pd-catalyzed cross-coupling of primary and secondary amines with halo-7-azaindoles(pyrrolo[2,3-b]pyridine) are presented. Previously, no general method was available to ensure the highly selective reaction of the heteroaryl halide in the presence of the unprotected azaindole N-H. Using palladium precatalysts recently reported by our group, such reactions are easily accomplished under mild conditions that can be applied to cross-coupling reactions with a wide array of aliphatic and aromatic amines.en_US
dc.description.sponsorshipAmgen, Inc.en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (Grant number GM-58160)en_US
dc.language.isoen_US
dc.publisherAmerican Chemical Society (ACS)en_US
dc.relation.isversionofhttp://dx.doi.org/10.1021/ol101928men_US
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en_US
dc.sourcePMCen_US
dc.titlePalladium-Catalyzed Amination of Unprotected Halo-7- azaindolesen_US
dc.typeArticleen_US
dc.identifier.citationHenderson, Jaclyn L., Sarah M. McDermott, and Stephen L. Buchwald. “Palladium-Catalyzed Amination of Unprotected Halo-7-azaindoles.” Organic Letters 12.20 (2010): 4438–4441.en_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemistryen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Humanities. History Sectionen_US
dc.contributor.approverBuchwald, Stephen L.
dc.contributor.mitauthorHenderson, Jaclyn L.
dc.contributor.mitauthorMcDermott, Sarah M.
dc.contributor.mitauthorBuchwald, Stephen Leffler
dc.relation.journalOrganic Lettersen_US
dc.eprint.versionAuthor's final manuscripten_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsHenderson, Jaclyn L.; McDermott, Sarah M.; Buchwald, Stephen L.en
dc.identifier.orcidhttps://orcid.org/0000-0003-3875-4775
mit.licensePUBLISHER_POLICYen_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record