Browsing MIT Libraries by Title
Now showing items 25070-25089 of 61802
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Genesis, dynamics, and dissipation of turbulent magnetic fields
(Massachusetts Institute of Technology, 2022-09)Astronomical observations indicate that coherent, dynamically important magnetic fields are ubiquitous in the Universe. However, neither the origin problem—what are the physical mechanisms that generate the initial ``seed'' ... -
Genesis-II : A language generation module for conversational systems
(Massachusetts Institute of Technology, 2000) -
A genetic algorithm for resource-constrained scheduling
(Massachusetts Institute of Technology, 1996) -
Genetic algorithms for uncapacitated network design
(Massachusetts Institute of Technology, 1995) -
Genetic analyses of the Rb and p53 genes in murine development and tumorigenesis
(Massachusetts Institute of Technology, 2005)The RB and p53 genes play central roles in cell cycle and checkpoint control, apoptosis and many other biological processes. These are central tumor suppressor genes that are each inactivated in many human cancers. Mouse ... -
Genetic Analysis of Bacterial Food Perception and its Influence on Foraging Behavior in C. elegans
(Massachusetts Institute of Technology, 2022-09)The ability to adapt to changes in food conditions is critical for organismal homeostasis and survival. In this thesis, I explore the genetic and neuroendocrine mechanisms by which C. elegans evaluates bacterial food ... -
Genetic analysis of cGMP-dependent chemosensory signal transduction pathways in the detection of bacterial metabolites by C. elegans
(Massachusetts Institute of Technology, 2019)The ability of metazoans to sense and interpret the external chemical environment is conferred by the chemosensory nervous system governing the senses of smell and taste. Chemosensory neurons convey external stimuli in the ... -
A genetic analysis of complexin function in neurotransmitter release and synaptic plasticity
(Massachusetts Institute of Technology, 2009)Information transfer at neuronal synapses requires rapid fusion of docked synaptic vesicles in response to calcium influx during action potentials. The molecular nature of the fusion clamp machinery that prevents exocytosis ... -
Genetic analysis of endoplasmic reticulum homeostasis during stress and infection of Caenorhabditis elegans
(Massachusetts Institute of Technology, 2018)Animals experience intrinsic and extrinsic stressors throughout development and adulthood. To maintain cellular and organismal homeostasis, eukaryota and metazoa rely on conserved, integrated stress response pathways. ... -
A genetic analysis of germ cell migration and gonadal mesoderm development in drosophila
(Massachusetts Institute of Technology, 1998) -
Genetic analysis of innate immunity in Caenorhabditis elegans
(Massachusetts Institute of Technology, 2007)Pathogen resistance in Caenorhabditis elegans is a model for studying innate immunity. Several conserved activators in the p38 PMK-1 pathway have been identified and are required for pathogen resistance to the bacterium ... -
Genetic analysis of longevity in Saccharomyces cerevisiae
(Massachusetts Institute of Technology, 2002)Aging is a universal process that affects organisms from yeast to humans. Replicative life span in the budding yeast, Saccharomyces cerevisiae is defined as the number of daughter cells produced by a mother cell prior to ... -
Genetic analysis of p38 mitogen-activated protein kinase signaling in innate immunity and stress physiology of Caenorhabditis elegans
(Massachusetts Institute of Technology, 2014)Host-microbe interactions play an important role in the physiology and evolution of animals. Interactions with microbes can generally be considered beneficial or pathogenic to the host. The ability of an organism to mount ... -
Genetic analysis of programmed cell death in Drosophila melanogaster
(Massachusetts Institute of Technology, 2002)The correct regulation of programmed cell death, or apoptosis, is critical for proper development and prevention of disease. Components of the molecular mechanisms that govern apoptosis are conserved among organisms as ... -
Genetic analysis of synaptogyrin function in the synaptic vesicle cycle
(Massachusetts Institute of Technology, 2012)Neuronal communication relies on the continual replenishment of synaptic vesicles that are primed for neurotransmitter release in response to action potentials. A vast array of proteins is required to mediate synaptic ... -
Genetic analysis of the development and functioning of the HSN neurons of caenorhabditis elegans
(Massachusetts Institute of Technology, 1989) -
Genetic analysis of the maintenance of neuronal morphology in Drosophila melanogaster
(Massachusetts Institute of Technology, 2006)Precise control of cellular morphology is critical for both the development and maintenance of nervous systems. In the developing Drosophila eye, normal photoreceptor cells establish and maintain a highly polarized ... -
Genetic analysis of the neuronal integrated stress response in developmental plasticity and organismal physiology of C. elegans
(Massachusetts Institute of Technology, 2017)The genetic study of the C. elegans dauer developmental decision has served as an experimental paradigm for understanding how environmental cues influence organismal physiology through evolutionarily conserved neuroendocrine ... -
A genetic analysis of the secretion of β-lactamase
(Massachusetts Institute of Technology, 1982) -
Genetic analysis of timing, morphology and degradation of cell corpses in C. elegans
(Massachusetts Institute of Technology, 1999)