Browsing MIT Libraries by Title
Now showing items 50978-50997 of 61744
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Single-Molecule Protein Sequencing (I) and Genetically Dominant mRNA Therapies to Combat Viral Evolution (II)
(Massachusetts Institute of Technology, 2022-05)Proteins serve critical structural and dynamic functional roles at the cellular level of all living organisms. Understanding protein contribution to biological function is critical and rests on having appropriate technologies ... -
Single-molecule studies of eukaryotic helicase loading
(Massachusetts Institute of Technology, 2016)Cells must duplicate their genomic content fully and accurately in each cell cycle to maintain cellular identity and ensure the viability of their progeny. The first step in eukaryotic DNA replication initiation is the ... -
Single-molecule studies of protein degradation and kinesin-8 motility
(Massachusetts Institute of Technology, 2015)Molecular machines drive living organisms out of equilibrium and perform critical functions in almost every aspect of cellular processes. They are mechanical enzymes transducing free energy stored in chemical forms to ... -
Single-molecule studies of the mechanism of eukaryotic helicase activation
(Massachusetts Institute of Technology, 2021)Eukaryotic DNA replication is a fundamental process that must occur accurately and only once per cell cycle. To ensure that origins only initiate once per cell cycle, the events of DNA replication initiation are temporally ... -
Single-molecule visualization of conformational changes in the SecA ATPase
(Massachusetts Institute of Technology, 2015)The need for new antibiotics is great as bacterial strains with single and multiple drug resistance have continued to grow more prevalent since the 1980's. At the same time, the rate of approval of new antibiotics has ... -
Single-nanocrystal photon correlation : a versatile tool for elucidating basic physics and characterizing applications-relevant properties
(Massachusetts Institute of Technology, 2015)Single-molecule spectroscopy has been a critical tool for the development and understanding of semiconductor nanocrystals because of their inherent heterogeneity size-dependent properties. In the past two decades, researchers ... -
Single-particle tracking and fluorescence correlation spectroscopy for systems-level analysis of molecular dynamics in diverse biological systems
(Massachusetts Institute of Technology, 2017)Fluorescence microscopy has proven to be immensely powerful for the study of biological systems at both the cellular and systems biological levels. The ability to specifically label a single molecular species fluorescently ... -
A single-pass grid-based algorithm for clustering big data on spatial databases
(Massachusetts Institute of Technology, 2017)The problem of clustering multi-dimensional data has been well researched in the scientific community. It is a problem with wide scope and applications. With the rapid growth of very large databases, traditional clustering ... -
Single-petaled K-types and Weyl group representations for classical groups
(Massachusetts Institute of Technology, 2008)In this thesis, we show that single-petaled K-types and quasi-single-petaled K-types for reductive Lie groups generalize petite K-types for split groups. First, we prove that a Weyl group algebra element represents the ... -
Single-photon detection of 1.55 [mu]m entangled light and frequency upconversion in periodically poled lithium niobate for quantum communication
(Massachusetts Institute of Technology, 2002) -
Single-photon frequency upconversion for long-distance quantum teleportation and communication
(Massachusetts Institute of Technology, 2006)Entanglement generation, single-photon detection, and frequency translation that preserves the polarization quantum state of the photons are essential technologies for long distance quantum communication protocols. This ... -
Single-Server Private Information Retrieval with Sublinear Amortized Time
(Massachusetts Institute of Technology, 2022-05)We construct new private-information-retrieval protocols in the singleserver setting. Our schemes allow a client to privately fetch a sequence of database records from a server, while the server answers each query in average ... -
Single-shot quantitative interferometric microscopy for imaging high-speed dynamics
(Massachusetts Institute of Technology, 2021-06)The observations of millisecond, micrometer-scale dynamical events are essential, especially in cell biology investigations, material science studies and the development of next-generation clinical diagnosis methods. For ... -
Single-shot spectroscopy of solid-state photoinduced dynamics far from equilibrium
(Massachusetts Institute of Technology, 2013)Ultrafast single-shot spectroscopy was developed and improved as a method to observe photoinduced dynamics far from equilibrium. The method was then employed to illuminate material dynamics in platinum-halide quasi-one-dimensional ... -
Single-sided natural ventilation : design analysis and general guidelines
(Massachusetts Institute of Technology, 2001)Natural ventilation is an effective measure to save energy consumed in buildings and to improve indoor air quality. This study focuses specifically on the principles of single-sided natural ventilation design. Single-sided ... -
Single-site, noninvasive, blood pressure measurements at the ear using ballistocardiogram (BCG), and photoplethysmogram (PPG), and a low-power, reflectance-mode PPG SoC
(Massachusetts Institute of Technology, 2014)This work presents a wearable congestive heart failure (CHF) monitor at the ear that uses the ballistocardiogram (BCG), electrocardiogram (ECG), and photoplethysmogram (PPG) to extract mean blood pressure up the Carotid ... -
Single-use lancet and capillary loading mechanism for complete blood count point of care device
(Massachusetts Institute of Technology, 2011)As part of the development of a point of care complete blood count device, I designed a single use lancet integrated with a blood collection mechanism and interface and successfully tested a prototype. High speed video was ... -
Single-walled carbon nanotubes as near infrared fluorescent sensors : characterization, biological and analytical applications
(Massachusetts Institute of Technology, 2010)Reactive oxygen species (ROS) have emerged as biological signaling molecules, participating in newly discovered cascades that govern cell proliferation, migration, and pathogenesis. A major challenge in understanding these ... -
Singlet exciton fission : applications to solar energy harvesting
(Massachusetts Institute of Technology, 2014)Singlet exciton fission transforms a single molecular excited state into two excited states of half the energy. When used in solar cells it can double the photocurrent from high energy photons increasing the maximum ... -
Singlet exciton fission, a multi-exciton generation process, in organic semiconductor solar cells
(Massachusetts Institute of Technology, 2012)Organic semiconductor photovoltaics hold the promise of cheap production and low manufacturing setup costs. The highest efficiency seen in research labs, ~10% today, is still too low for production. In this work we explore ...
