Browsing MIT Libraries by Title
Now showing items 22716-22735 of 57437
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Function and regulation of poly(A)-tail length
(Massachusetts Institute of Technology, 2014)Poly(A) tails are found at the 3' ends of nearly all eukaryotic messenger RNAs (mRNAs) and long non-coding RNAs. The presence of a poly(A) tail promotes translation and inhibits decay of an mRNA, with both effects mediated ... -
Function follows form : how connectivity patterns govern neural responses
(Massachusetts Institute of Technology, 2013)Connectivity restricts and defines the information that a network can process. It is the substance of information processing that underlies the patterns of functional activity in the brain. By combining diffusion-weighted ... -
The function of E2F6 in the Polycomb complex
(Massachusetts Institute of Technology, 2005)The E2F family of transcription factors are known cell cycle regulators that function at the G1/S transition. Unlike other E2Fs, E2F6 does not activate transcription and is not regulated by pocket protein binding. Instead, ... -
The function of leisure in the urban environment
(Massachusetts Institute of Technology, 1960) -
The function of repetition in typology
(Massachusetts Institute of Technology, 1988)The purpose of this thesis will be to attempt an analogy between the topography of architectural production, as witnessed by the evolution and employment of architectural typologies, and the topography of mental production, ... -
The function of testing during architectural design.
(Massachusetts Institute of Technology, 1971) -
The function of the fornix in Syrian golden hamsters : a lesion and behavioral study of the Papez circuit
(Massachusetts Institute of Technology, 2002) -
Function-based indexing for object-oriented databases
(Massachusetts Institute of Technology, 1994) -
Functional "backpacks" for cellular engineering
(Massachusetts Institute of Technology, 2010)Polymer multilayers may be built through the sequential ("layer-by-layer") adsorption of species (polymers, nanoparticles) with specific interactions (electrostatic, hydrogen-bonding). Multilayered heterostructures - films ... -
Functional activation of the p53 tumor suppressor in non-tumorigenic variants of the HeLa cervical carcinoma cell line
(Massachusetts Institute of Technology, 1996) -
Functional analyses of mitotic microtubule-binding complexes
(Massachusetts Institute of Technology, 2018)Mitosis is the process by which a single cell divides to form two identical daughter cells. Each daughter cell must inherit a full complement of the genetic material. Thus, a critical aspect of mitosis is the faithful ... -
Functional analysis of a class II aminoacyl-tRNA synthetase
(Massachusetts Institute of Technology, 1994) -
Functional analysis of K-ras in the mouse by gene targeting
(Massachusetts Institute of Technology, 1996) -
Functional analysis of middle temporal visual area and its associated behavior
(Massachusetts Institute of Technology, 2002)Our lab's long-term goal is to elucidate the circuitry of the visual cortex, to develop quantitative computational models of neuronal function in the visual cortex, and to establish how these models may relate to visual ... -
Functional analysis of systems characterized by nonlinear differential equations.
(Massachusetts Institute of Technology, 1966) -
Functional analysis of the histone variant H2A.Z during lineage commitment
(Massachusetts Institute of Technology, 2014)remained enigmatic. In this thesis, we dissect the role of H2A.Z during lineage commitment. In particular, we focused on the Polycomb-mediated mono-ubiquitylation of H2A.Z. We found that this modification regulates the ... -
Functional analysis of the microRNA genes of C. elegans
(Massachusetts Institute of Technology, 2008)MicroRNAs (miRNAs) were discovered in C. elegans during studies of the control of developmental timing. MicroRNAs are a large class of short non-coding RNAs found in many viruses, plants and animals that regulate gene ... -
Functional analysis of the Neurofibromatosis Type II tumor suppressor gene
(Massachusetts Institute of Technology, 1999) -
Functional and computational analysis of RNA-binding proteins and their roles in cancer
(Massachusetts Institute of Technology, 2014)This work is concerned with mRNA processing in mammalian cells and proceeds in two parts. In the first part, I introduce a computational framework for inferring the abundances of mRNA isoforms using high-throughput RNA ... -
Functional and cross-trait genetic architecture of common diseases and complex traits
(Massachusetts Institute of Technology, 2017)In this thesis, I introduce new methods for learning about diseases and traits from genetic data. First, I introduce a method for partitioning heritability by functional annotation from genome-wide association summary ...
