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Use Of synthetic solid scaffolds to mechanically support a chondrocyte-seeded peptide hydrogel for articular cartilage repair
(Massachusetts Institute of Technology, 2017)
Post-traumatic osteoarthritis (PTOA) is a subtype of OA associated with cartilage defects caused by traumatic joint injury. Because articular cartilage has a limited innate healing response, due to its avascular, aneural, ...
Tau aggregation is heterogeneous across cases of sporadic Alzheimer's disease and is influenced by autophagy pathways in vitro
(Massachusetts Institute of Technology, 2020)
Tau neurofibrillary tangles or aggregates are a common neuropathological feature found in a number of neurodegenerative conditions, including Alzheimer's disease. Understanding the kinetics of this aggregate build up, how ...
Integration of metabolic modelling with machine learning to identify mechanisms underlying antibiotic killing
(Massachusetts Institute of Technology, 2017)
Microbial pathogens are becoming a pressing global health issue due to the rapid appearance of resistant strains, accompanied by slow development of new antibiotics. In order to improve these treatments and engineer novel ...
Development of a microfluidic droplet system for immune Cell multiplexing experimentation
(Massachusetts Institute of Technology, 2019)
An incredibly intricate system composed of many dierent cell types, tissues, and molecules, the immune system is integral to a body's health and well-being. Yet, with the multitude of components present within the system ...