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Now showing items 191-200 of 200
An analysis and mitigation of demand variability on external supply chains
(Massachusetts Institute of Technology, 2019)
In the pharmaceutical industry, increasing product complexity, shifts towards specialty medicine and growth in emerging markets have resulted in increased forecast variation and manufacturing complexity for new products. ...
Electricity sensors for resource efficiency and supply chain visibility in factories
(Massachusetts Institute of Technology, 2019)
Cost pressures on factories and the growing movement towards sustainability are key motivations behind Li & Fung's (LF) drive towards innovation. Supply chain digitalization through initiatives such as the Internet of ...
Improving customer experience by better predicting revised delivery dates
(Massachusetts Institute of Technology, 2019)
Historically, Dell has used a variety of methods to calculate a customer order's initial Estimated Delivery Date (EDD) and a subsequent Revised Delivery Date (RDD) as necessary. Multiple tools arose to meet diverse business ...
Optimization of downstream supply chain product flow based on an integrated cost-to-deliver perspective
(Massachusetts Institute of Technology, 2019)
As Boston Scientific's supply chain becomes more versatile in mixing their supply networks across divisions, there is new opportunity to re-optimize product flow downstream of manufacturing based on unique product attributes ...
improving contact lens manufacturing through cost modeling and batch production scheduling optimization
(Massachusetts Institute of Technology, 2019)
J&J Vision Care (JJVC) uses production scheduling methods that are not fully optimized, causing over-production of certain SKUs, and reducing capacity for other SKUs on backorder. This makes planning a weekly run-schedule ...
Predictive earthquake damage modeling for natural gas distribution infrastructure
(Massachusetts Institute of Technology, 2018)
The Pacific Gas and Electric Company (PG&E) operates and maintains 48,000 miles of natural gas pipeline, serving over 4.3 million customer accounts. Along with water, electric power, and transportation services, these ...
Oral drug delivery as an alternative to needle-based injection for large molecules : an assessment of the field & evaluation of high-priority technologies
(Massachusetts Institute of Technology, 2018)
Oral delivery of large molecules is widely considered the "holy grail" of drug delivery, but attempts to achieve this within the past century have been met with a lack of success, confounded by low bioavailability. Novel ...
Organizational architecture design and assessment of statistical feasibility for FSDA implementation in an airplane subassembly
(Massachusetts Institute of Technology, 2020)
Boeing is a ubiquitous name and prominent leader in the aerospace industry, maintaining dominance in part by continuously seeking to improve. Boeing is now embracing a charter to become a Global Industrial Champion in ...
Container removal and replacement automation : design and development of robotic work cells for warehouse automation
(Massachusetts Institute of Technology, 2019)
Amazon has grown at a rapid pace. In 2018, Amazon retail sales amounted to $141.92B, up 19.7% from the previous year. The number of units shipped through its Prime program alone grew by 20% from 5 billion the previous year ...
Project-based manufacturing : an approach for quote development
(Massachusetts Institute of Technology, 2020)
Project-based manufacturing presents unique challenges that highly automated and repetitive production lines do not face. Highly automated production lines do not have much variation in the types of products that are made, ...