Search
Now showing items 21-30 of 40
Evaluation of automated storage and retrieval in a distribution center
(Massachusetts Institute of Technology, 2020)
In the face of e-commerce growth and rising customer delivery expectations, companies must adapt to meet shorter contract shipping requirements with existing infrastructures. The "Amazon effect", an evolution resulting in ...
Reducing variations in a highly constrained environment in order to increase production capacity
(Massachusetts Institute of Technology, 2020)
Variations and the negatives effects it causes on production capacity and planning are topics of significant interest in the manufacturing communities. This research investigates the hypothesis that, when operating in a ...
Developing a robust harvest for high cell density CHO cell culture
(Massachusetts Institute of Technology, 2020)
Increasing e-commerce distribution center capacity through slotting strategy
(Massachusetts Institute of Technology, 2020)
To meet increasing consumer expectations around delivery times, ecommerce retailers must take orders from 'click' to 'ship' as soon as possible. For retailers with tens of thousands of stock keeping units (SKUs), item ...
Predictive analysis of installation and operational qualification issues vs. process severity events
(Massachusetts Institute of Technology, 2020)
As the retail industry grows more popular, ABCD, a world-class electronic commerce (e-commerce) business, is increasingly building new Fulfillment Centers (FCs) to support this rapid demand growth. It is integral for ABCD ...
Strategic capacity planning using data science, optimization, and machine learning
(Massachusetts Institute of Technology, 2020)
Raytheon's Circuit Card Assembly (CCA) factory in Andover, MA is Raytheon's largest factory and the largest Department of Defense (DOD) CCA manufacturer in the world. With over 500 operations, it manufactures over 7000 ...
Leveraging flexible manufacturing to streamline new product launch processes
(Massachusetts Institute of Technology, 2020)
Johnson & Johnson Vision (JJV), manufacturer of the ACUVUE® Brand Contact Lenses, is committed to launching new contact lens products every year to maintain competitive edge and long-term relevancy. However, manufacturing ...
Computation and predictive modeling to increase efficiency and performance in cell line and bioprocess development
(Massachusetts Institute of Technology, 2020)
A critical early step in the development of a new biopharmaceutical is the selection of the master cell bank. Per FDA requirements, the same master cell bank must be used for all toxicity and clinical trials, as well as ...
Inventory modeling for active pharmaceutical ingredient supply chains
(Massachusetts Institute of Technology, 2020)
Pharmaceutical companies traditionally manufactured drugs in-house, and have only recently been increasingly outsourcing production to contract manufacturing organizations (CMOs). In this work, we use inventory modeling ...
Integrating agile within complex hardware development via additive manufacturing
(Massachusetts Institute of Technology, 2020)
A major benefit of Additive Manufacturing (AM) is a faster timeline from design to fabrication. As AM has matured to be able to create functional prototypes and end-use products, the ability to quickly fabricate physical ...