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Multi-modal, multi-period, multi-commodity transportation : models and algorithms
(Massachusetts Institute of Technology, 2014)
In this paper we present a mixed integer optimization framework for modeling the shipment of goods between origin destination (O-D) pairs by vehicles of different types over a time-space network. The output of the model ...
Column generation approaches to the military airlift scheduling problem
(Massachusetts Institute of Technology, 2014)
In this thesis, we develop methods to address airlift scheduling, and in particular the problem of scheduling military aircraft capacity to meet ad hoc demand. Network optimization methods typically applied to scheduling ...
Estimating network structure and propagation dynamics for an infectious disease : towards effective vaccine allocation
(Massachusetts Institute of Technology, 2014)
In the event of a pandemic influenza outbreak, such as the 2009-2010 H1N1 "Swine Flu" episode, it is crucial to effectively allocate limited resources in order to minimize the casualties. Design of effective resource ...
An analytics approach to hypertension treatment
(Massachusetts Institute of Technology, 2014)
Hypertension is a major public health issue worldwide, affecting more than a third of the adult population and increasing the risk of myocardial infarction, heart failure, stroke, and kidney disease. Current clinical ...
Optimized border interdiction
(Massachusetts Institute of Technology, 2014)
A feature of many conflicts is the presence of a border that separates an area of on-going military operations from an area that the enemy can use permissively. This thesis considers analytic techniques for planning military ...
Extracting product opportunities from intellectual property portfolios : from patent to product idea
(Massachusetts Institute of Technology, 2014)
Companies and research institutes maintain large intellectual property portfolios, which are considered company assets and require significant investments to maintain. This thesis looks at the potential to extract value ...
Determining appropriate levels of robotic automation in commercial aircraft nacelle assembly
(Massachusetts Institute of Technology, 2014)
This thesis examines the application of reconfigurable industrial robotics in the assembly of the engine nacelle inlet for a commercial aircraft. In addition to addressing the achievable level of automation, this thesis ...
Complexity cost quantification and modeling for strategic portfolio management
(Massachusetts Institute of Technology, 2014)
This project explores portfolio management and planning through effectively reducing complexity within operations. We apply this to a major healthcare company (referred to as Company X). The anticipated launch of new ...
Priority queuing for raw material receiving
(Massachusetts Institute of Technology, 2014)
The Amgen Manufacturing Ltd. facility in Juncos, Puerto Rico faces a challenge encountered by manufacturers across industries: How can they make the best use of their existing resources? As production volume and product ...
Forecasting linehaul transit times & on time delivery probability using quantile regression forests
(Massachusetts Institute of Technology, 2014)
with delays on the road and variabilities introduced by the major participants in the process, ie: distribution centers, drivers, etc. These sources of variability also make it difficult to measure the impact changes in ...