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Radiation therapy of pediatric brain tumors : comparison of long-term health effects and costs between proton therapy and IMRT
(Massachusetts Institute of Technology, 2011)
Radiation therapy is an important component of pediatric brain tumor treatment. However, radiation-induced damage can lead to adverse long-term health effects. Proton therapy has the ability to reduce the dose delivered ...
Metal price volatility : a study of informative metrics and the volatility mitigating effects of recycling
(Massachusetts Institute of Technology, 2011)
Metal price volatility is undesirable for firms that use metals as raw materials, because price volatility can translate into volatility of material costs. Volatile material costs and can erode the profitability of the ...
Unique abilities of hopper spacecraft to enable national objectives for solar system exploration
(Massachusetts Institute of Technology, 2011)
In comparison with conventional and other conceived approaches, hopper spacecraft offer unique advantages in exploring Solar System objects beyond Earth. The present work began with a survey - based on documents from the ...
A semantic data federation engine : design, implementation & applications in educational information management
(Massachusetts Institute of Technology, 2011)
With the advent of the World Wide Web, the amount of digital information in the world has increased exponentially. The ability to organize this deluge of data, retrieve it, and combine it with other data would bring numerous ...
A cost model for testing unmanned and autonomous systems of systems
(Massachusetts Institute of Technology, 2011)
The evolutionary nature of Unmanned and Autonomous Systems of Systems (UASoS) acquisition needs to be matched by equally evolutionary test capabilities in the future. There is currently no standard method to determine what ...
Tragedy of the routing table : an analysis of collective action amongst Internet network operators
(Massachusetts Institute of Technology, 2011)
This thesis analyzes and discusses the effectiveness of social efforts to achieve collective action amongst Internet network operators in order to manage the growth of the Internet routing table. The size and rate of growth ...
Addressing design challenges in mechanical counterpressure spacesuit design and space-inspired informal education policy
(Massachusetts Institute of Technology, 2011)
Extravehicular activity (EVA), or spacewalks allows astronauts to accomplish some of the most important endeavors in space history. The importance of EVA will continue to increase as people venture further into our solar ...
Assessing and reducing product portfolio complexity in the pharmaceutical industry
(Massachusetts Institute of Technology, 2011)
Overly complex product portfolios lead to inefficient use of resources and limit an organization's ability to react quickly to changing market dynamics. The challenges of reducing portfolio complexity are defining excess ...
Process management applications in biopharmaceutical drug production
(Massachusetts Institute of Technology, 2011)
Genzyme's manufacturing and supply chain organization is responsible for the production and delivery of medically necessary medicines for patients with rare diseases around the world. Because of the nature of the products ...
Managing variability to improve quality, capacity and cost in the perioperative process at Massachusetts General Hospital
(Massachusetts Institute of Technology, 2011)
The widely held assumption is that to improve access and quality of health care, we need to spend more. In fact, that is not necessarily true. The results of this project, performed at Massachusetts General Hospital (MGH), ...