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A computational framework for predicting CHO cell culture performance in bioreactors
(Massachusetts Institute of Technology, 2019)
Breaking the trade-off between speed and productivity is a key milestone across industries. In particular, in the biopharmaceutical industry this trade-off is exacerbated by a highly regulated environment, which hinders ...
Developing a robust harvest for high cell density CHO cell culture
(Massachusetts Institute of Technology, 2020)
Crystal ball planning for analytics implementation in Singapore
(Massachusetts Institute of Technology, 2014)
Amgen is building a new drug substance manufacturing site in Singapore (ASM). This project identified and mitigated the risks associated with implementing analytical technologies to facilitate the design and implementation ...
Streamlining and standardizing transcriptomic analysis in Amgen process development
(Massachusetts Institute of Technology, 2016)
Building biological understanding of the Chinese Hamster Ovary (CHO) system used to manufacture therapeutic proteins is paramount to efficient CHO bioprocess optimization. This understanding can be built by analyzing and ...