Search
Now showing items 181-190 of 200
Impact of product design choices on supply chain performance in the notebook computer industry
(Massachusetts Institute of Technology, 2010)
Intel Corporation is the world's leading manufacturer of processors for personal computers. As the company strives to maintain its leadership position in this industry, it identifies significant trends in the industry and ...
Developing biotechnology company's future positioning strategy in prefilled syringe market
(Massachusetts Institute of Technology, 2010)
The primary goal for the thesis is to develop a recommendation for Amgen's future prefilled syringe strategy related to its drug process development, supplier relationship management plan, supply and sourcing, and procurement. ...
Enabling effective lifecycle management of manufacturing facilities with enhanced decision making processes
(Massachusetts Institute of Technology, 2017)
As a global manufacturing company, Company X has built up an extensive and varied portfolio of manufacturing facilities. These facilities vary greatly in capability, age, and performance. This creates difficulties in ...
Lean principles in an aircraft assembly process
(Massachusetts Institute of Technology, 2018)
A universal imperative of most manufacturing firms is to lower cost, increase production rate, and deliver exceptional quality for every product. The manufacturing firm that springs to mind as the standard bearer for all ...
Quantifying the business case for aerospace assembly automation
(Massachusetts Institute of Technology, 2017)
As aerospace Original Equipment Manufacturer's (OEM's) order backlogs soar to between six to ten years and growing, the community sees automation as vital to increasing throughput. Yet the community seems divided on the ...
Implementation of a manufacturing technology roadmapping initiative
(Massachusetts Institute of Technology, 2012)
Strategic technology planning is a core competency of companies using technological capabilities for competitive advantage. It is also a competency with which many large companies struggle due to the cross-functional ...
Reducing total fulfillment costs through distribution network design optimization
(Massachusetts Institute of Technology, 2013)
Compared to legacy retailers, online retailers have the potential to better accommodate buyer needs by offering more service time and inventory options. One fundamental operational challenge faced by most online businesses ...
Simulation and optimization of outbound operations in an e-grocer's warehouse
(Massachusetts Institute of Technology, 2018)
A second wave of online grocery retailers ("e-grocers") emerged in late 2000's after dot.com companies, such as Webvan, Streamline and Homegrocer, failed to break into the grocery market despite investing heavily on automated ...
Enhancing the design and procurement of single-use assemblies in biomanufacturing by implementing modular specifications
(Massachusetts Institute of Technology, 2018)
Usage of single-use systems (SUS) in biomanufacturing has expanded rapidly in recent years. Amgen uses SUS at several commercial manufacturing sites, in addition to pilot plants and clinical production. Each single-use ...
Evaluation of predictive computational modelling in biologic formulation development
(Massachusetts Institute of Technology, 2017)
Computational modelling has completely redefined the experimentation process in many industries, allowing large sets of design concepts to be tested quickly and cheaply very early in the innovation process. Harnessing the ...