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Now showing items 11-20 of 45
Integrated decision support model for global sourcing
(Massachusetts Institute of Technology, 2008)
Over the last decade, the U.S. aircraft industry has experienced increasing levels of international integration as companies seek to access global talent and resources, cut production costs, spread financial risk, and ...
Lean transformation of a supply chain organization
(Massachusetts Institute of Technology, 2008)
There are two basic schools of thought regarding how to approach a Lean transformation. Either start with introducing Lean tools or start with driving a Lean cultural change. Academic researchers like Steve Spear (Harvard/MIT), ...
Investigating late stage biopharmaceutical product loss using novel analytical and process technology
(Massachusetts Institute of Technology, 2008)
The biopharmaceutical industry uses recombinant protein technologies to provide novel therapeutics to patients around the world. These technologies have presented exciting opportunities for breakthrough medical treatments ...
Designing and implementing auxiliary operational processes
(Massachusetts Institute of Technology, 2008)
Amazon.com, one of the largest and most profitable online retailers, has been experiencing such dramatic growth rates that it must continually update and modify its fulfillment process in order to meet customer demand for ...
Evaluating cost-reduction alternatives and low-cost sourcing opportunities for aerospace castings and forgings
(Massachusetts Institute of Technology, 2008)
As companies continue to outsource large portions of their manufacturing, managing costs in the supply chain is increasingly important in reducing overall costs and remaining competitive. Low-cost sourcing has become an ...
Using Virtual Business Systems to drive lean behavior in engineering design and support
(Massachusetts Institute of Technology, 2008)
Virtual Business System (VBS) is a visual-based analytics and real-time information displaying system. It first started at Raytheon's Andover manufacturing facility in early 2000 with the strategic objectives of linking ...
Development of a total landed cost and risk analysis model for global strategic sourcing
(Massachusetts Institute of Technology, 2008)
Total landed cost and supply chain risk analysis are methods that many companies use to assess strategic sourcing decisions. For this project, landed cost is defined as those costs associated with material movement from a ...
Achieving business and operational excellence in the pharmaceutical industry
(Massachusetts Institute of Technology, 2008)
Historically the pharmaceutical industry has been highly profitable. However, the increasing regulatory requirements, bargaining power of buyers, and drug failures together with the threat of biosimilars and decreasing R&D ...
Development of a global facility location analysis tool
(Massachusetts Institute of Technology, 2008)
With an economy and customer base that is global, companies are increasingly expanding outside their home country's borders. Many times this is done to take advantage of lower labor or material rates, to increase proximity ...
Cycle time reduction through wafer starts control
(Massachusetts Institute of Technology, 2008)
Intel's Fab 17, located in Hudson, Massachusetts, has experienced dramatic improvements in its cycle time performance in the last two years. These improvements have been attributed to lean implementation efforts, reduced ...