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Now showing items 11-20 of 20
Extracting product opportunities from intellectual property portfolios : from patent to product idea
(Massachusetts Institute of Technology, 2014)
Companies and research institutes maintain large intellectual property portfolios, which are considered company assets and require significant investments to maintain. This thesis looks at the potential to extract value ...
Improving the inbound supply chain through dynamic pickup windows
(Massachusetts Institute of Technology, 2014)
Amazon is one of the world's largest retailers with revenues of $74.5 billion in 2013 and 22% growth over 2012. As Amazon continues to grow and offer greater selection, more products are flowing through an expanding inbound ...
Framework and strategies for reducing aircraft lead time
(Massachusetts Institute of Technology, 2014)
Aircraft are complex machines consisting of tens of thousands of parts and assemblies. Due to special engineering requirements, processes, and materials, the lead time for many of the parts can be several months resulting ...
External operations portfolio analysis and segmentation
(Massachusetts Institute of Technology, 2014)
This thesis focuses on a medical device manufacturer, Company X, using a razor-and-blades business strategy, in which surgical instruments are offered to customers at little or no cost in order to facilitate the sale of ...
A practical application of simulation for production planning in a flexible pharmaceutical manufacturing environment
(Massachusetts Institute of Technology, 2014)
In pursuit of Novartis Pharmaceutical's vision to "Make Quality Medicine-On Time, Every Time" Novartis Ringaskiddy Limited (NRL), is pursuing Class A Manufacturing (MRP II) certification. Achieving Class A certification ...
Forecasting linehaul transit times & on time delivery probability using quantile regression forests
(Massachusetts Institute of Technology, 2014)
with delays on the road and variabilities introduced by the major participants in the process, ie: distribution centers, drivers, etc. These sources of variability also make it difficult to measure the impact changes in ...
Creating a corporate strategy for utilizing supply chain simulation, optimization and visualization
(Massachusetts Institute of Technology, 2014)
Computer based supply chain simulation, optimization, and visualization capability have changed significantly in the past 45 years, expanding capability in lockstep with increases in computational power. The increase in ...
Streamlining data management in drug product commercialization and manufacturing
(Massachusetts Institute of Technology, 2014)
Effective execution and alignment of data management across development and manufacturing teams is essential for Amgen's Drug Product Technology group to realize its main goals of shortening the development timeline and ...
Tactical planning optimization for campaign scheduling of active pharmaceutical ingredient production based on monoclonal antibodies
(Massachusetts Institute of Technology, 2014)
Monoclonal Antibodies (mAb's) are the fastest growing segment in the biopharmaceutical industry. They are used today as therapeutics and diagnostics for several medical applications, including various types of cancer, ...
Inventory management for perishable goods using simulation methods
(Massachusetts Institute of Technology, 2014)
Amazon.com is the world's largest online retailer, and continues to grow its business by expanding into new markets and new product lines that have not traditionally been sold online. These product categories create new ...