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Now showing items 11-20 of 51
Lean transformation methodology and implementation in biopharmaceutical operations
(Massachusetts Institute of Technology, 2008)
Amgen's Operations division is responsible for the production, release and distribution of commercial and clinical products. Due to industry consolidation, impending competition and revenue impacts, Amgen is facing the ...
A "go to market" strategy : enabling P&G profitable share growth through streamlined logistics
(Massachusetts Institute of Technology, 2002)
The cosmetics industry is an intensely competitive, fashion-driven industry. As such, new product launch processes are viewed to be a competitive advantage in promoting continued brand awareness in the market place. However, ...
The DNA of a high-performing manufacturing organization : improving operations capability through performance measurement
(Massachusetts Institute of Technology, 2006)
The Broad Institute of MIT, Harvard, and the Whitehead Institute, contains the world's highest-throughput genome sequencing center, which contributed approximately one third of the sequence for the Human Genome Project ...
A framework for analyzing biopharmaceutical product introduction in an emerging market
(Massachusetts Institute of Technology, 2006)
Biopharmaceutical companies are under constant pressure to deliver double-digit growth. In traditional markets such as the U.S., Japan, and the European Union growth is stagnant, and profit margins are falling due to ...
Integrating cost consequences into a high quality manufacturing environment
(Massachusetts Institute of Technology, 2003)
Intel Corporation, the world leader in manufacturing microprocessors, has beer successful in achieving high margins because of its ability to successfully deliver high volume and reliable microprocessors at high demand. ...
Analysis of variability in the semiconductor industry
(Massachusetts Institute of Technology, 2004)
While the pace of technical innovation in the semiconductor industry continues to accelerate, business processes and supply chain techniques have not kept up. Microprocessor performance improvement continues to follow ...
Implementation of new technology in a regulated environment
(Massachusetts Institute of Technology, 2004)
This thesis investigates potential improvements to the manufacturing process through the implementation of process analytical technologies (PAT) in the heavily regulated pharmaceutical industry. The thesis focuses on the ...
A comparative analysis of diagnostic tools and techniques for manufacturing business support
(Massachusetts Institute of Technology, 2004)
The overriding objective of diagnostic assessment is change. Assessment processes are a mechanism to identify areas that merit change. In order to maximize the possibility that a company will adopt recommended changes ...
Batch sizing strategy & production load leveling in a multi-step chemical manufacturing process
(Massachusetts Institute of Technology, 2005)
In the last couple of years Eastman Kodak Company went through major changes in its strategic direction. The same disruptive technologies that they helped develop for digital imaging have shaped a new industry, and the ...
Optimization of preclinical profiling operations in drug discovery
(Massachusetts Institute of Technology, 2007)
In early-stage drug discovery, thousands of compounds must be tested using in vitro assays to determine their exposure and safety characteristics. This data is used to guide the selection of potential drug candidates and ...